individuals with COPD have shown to have increased airway expressions of ACE-2 (106). It is still worth mentioning that patients who have this type of disorder often use corticosteroid immune-suppressing drugs, whose effect of reducing the immunity to respiratory infections may represent another contributing factor to a higher risk of infection (107).

Clinical and Radiological Changes
Most COVID-19 patients exhibit mild to moderate symptoms, but approximately 15% progress to c