the S complex, resulting in the release of the S1 subunit and activation of S2 fusogenic activity (55). The S2 subunit contains an N-terminal fusion peptide (FP), heptad repeat 1 (HR1), heptad repeat 2 (HR2), a transmembrane region (TM), and a cytoplasmic tail (CT). During the fusion process, the FP portion is exposed and inserts into the membrane of the target cell, le