Selenium Fish, shellfish, meat, eggs, some nuts especially brazil nuts ↑ IFN-γproduction Selenoproteins important for antioxidant host defense system, affecting leukocyte and NK cell function Essential for function of selenoproteins that act as redox regulators and cellular antioxidants, potentially counteracting ROS produced during oxidative stress Roles in differentiation and proliferation of T cells ↑ Th cell counts and to maintain antibody levels [82, 85, 92, 95]