uent of the anaphase promoting complex/cyclosome, which is an E3 ubiquitin ligase that regulates the temporal progression of eukaryotic cells by mediating ubiquitination and subsequent 26S proteasome-mediated degradation of key cell cycle regulators.39 The downregulation of ANAPC7 is indicative of dysfunction of IPEC-J2 cells caused by PDCoV infection. IFIT1 is an