ine endemic diarrhea virus (PEDV),13 and transmissible gastroenteritis virus (TGEV).14 Recently, Jung and colleagues demonstrated that IPEC-J2 cells are quite susceptible to PDCoV infection in vitro.8 As a newly emerged swine enteropathogenic coronavirus, the pathogenic mechanisms of PDCoV are still poorly documented and warrant further exploration.1 It is well-kn