SMW-Solute Molecular weight, D- Solute dipole moment, QPlog P- QP log P for octanol/water, QPlog S - QP log S for aqueous solubility, LogKhsa -QP log K hsa Serum Protein Binding, Log BB - QP log BB for brain/blood, PM: No of primary metabolites, Caco- Apparent Caco-2 Permeability (nm/sec), Rule of 5 - Lipinski Rule of 5 Violations, Rule of 3- Jorgensen Rule of 3 Violations, OA- % Human Oral Absorption in GI.