2 D structures of the constituents of N. sativa obtained from PubChem. (a) 2719 (Chloroquine), (b) 6654 (Alpha-pinene), (c) 7463 (P-cymene), (d) 3652 (Hydroxychloroquine), (e) 10281 (Thymoquinone), (f) 10364 (Carvacrol), (g) 11230 (Terpinen-4-ol), (h) 398941 (Dithymoquinone), (i) 95779 (Thymohydroquinone), (j) 1796220 (Longifolene), (k) 73296 (alpha-Hederin), (l) 637563 (trans-Anethole), (m) 11402337 (Nigellicine), (n) 136828302(Nigellidine) A total of 12 bioactive constituents were retrieved namely thymoquinone, thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, longifolene, α-pinene, thymol, nigellidine, nigellicine and α-hederin (Figure 3).