PMC:7601109 / 98190-98808 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7601109","sourcedb":"PMC","sourceid":"7601109","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7601109","text":"Gavage CAPE (5 and 10 mg/kg/d/5 d) 6-7-weeks old male adult Wistar rats EG: CAPE + eccentric exerciseCG1: normal rats + propylene glycol in salineCG2: acute eccentric treadmill exercise Serum creatine kinase levels, IL-1β, MCP-1, COX-2, iNOS, leukocyte infiltration, and the extent of muscle fiber damage (vacuolization and fragmentation). CAPE decreased serum creatine kinase, protein nitrotyrosine, PARP activity, MDA, leukocyte infiltration, skeletal muscle cell fragmentation and vacuolization, muscle levels of COX2, iNOS, IL-1β, MCP-1, and p65NF-κB activity to levels in resting CG1 compared with CG2. 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