PMC:7601109 / 93962-94627 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T191","span":{"begin":301,"end":310},"obj":"Body_part"},{"id":"T192","span":{"begin":316,"end":333},"obj":"Body_part"},{"id":"T193","span":{"begin":316,"end":324},"obj":"Body_part"},{"id":"T194","span":{"begin":405,"end":418},"obj":"Body_part"},{"id":"T195","span":{"begin":483,"end":492},"obj":"Body_part"},{"id":"T196","span":{"begin":497,"end":514},"obj":"Body_part"},{"id":"T197","span":{"begin":497,"end":505},"obj":"Body_part"},{"id":"T198","span":{"begin":586,"end":599},"obj":"Body_part"}],"attributes":[{"id":"A191","pred":"uberon_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/UBERON_0011905"},{"id":"A192","pred":"uberon_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/UBERON_0001385"},{"id":"A193","pred":"uberon_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/UBERON_0008230"},{"id":"A194","pred":"uberon_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/UBERON_0001389"},{"id":"A195","pred":"uberon_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/UBERON_0011905"},{"id":"A196","pred":"uberon_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/UBERON_0001385"},{"id":"A197","pred":"uberon_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/UBERON_0008230"},{"id":"A198","pred":"uberon_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/UBERON_0001389"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T831","span":{"begin":27,"end":31},"obj":"Body_part"},{"id":"T832","span":{"begin":225,"end":227},"obj":"Body_part"},{"id":"T833","span":{"begin":293,"end":299},"obj":"Body_part"},{"id":"T834","span":{"begin":301,"end":310},"obj":"Body_part"},{"id":"T835","span":{"begin":316,"end":333},"obj":"Body_part"},{"id":"T836","span":{"begin":334,"end":341},"obj":"Body_part"},{"id":"T837","span":{"begin":366,"end":368},"obj":"Body_part"},{"id":"T838","span":{"begin":405,"end":418},"obj":"Body_part"},{"id":"T839","span":{"begin":483,"end":492},"obj":"Body_part"},{"id":"T840","span":{"begin":497,"end":514},"obj":"Body_part"},{"id":"T841","span":{"begin":515,"end":522},"obj":"Body_part"},{"id":"T842","span":{"begin":586,"end":599},"obj":"Body_part"}],"attributes":[{"id":"A831","pred":"fma_id","subj":"T831","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A832","pred":"fma_id","subj":"T832","obj":"http://purl.org/sig/ont/fma/fma284995"},{"id":"A833","pred":"fma_id","subj":"T833","obj":"http://purl.org/sig/ont/fma/fma22542"},{"id":"A834","pred":"fma_id","subj":"T834","obj":"http://purl.org/sig/ont/fma/fma22543"},{"id":"A835","pred":"fma_id","subj":"T835","obj":"http://purl.org/sig/ont/fma/fma22532"},{"id":"A836","pred":"fma_id","subj":"T836","obj":"http://purl.org/sig/ont/fma/fma32558"},{"id":"A837","pred":"fma_id","subj":"T837","obj":"http://purl.org/sig/ont/fma/fma284995"},{"id":"A838","pred":"fma_id","subj":"T838","obj":"http://purl.org/sig/ont/fma/fma22542"},{"id":"A839","pred":"fma_id","subj":"T839","obj":"http://purl.org/sig/ont/fma/fma22543"},{"id":"A840","pred":"fma_id","subj":"T840","obj":"http://purl.org/sig/ont/fma/fma22532"},{"id":"A841","pred":"fma_id","subj":"T841","obj":"http://purl.org/sig/ont/fma/fma32558"},{"id":"A842","pred":"fma_id","subj":"T842","obj":"http://purl.org/sig/ont/fma/fma22542"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1677","span":{"begin":39,"end":42},"obj":"http://purl.obolibrary.org/obo/CLO_0002675"},{"id":"T1678","span":{"begin":240,"end":250},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1679","span":{"begin":334,"end":341},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T1680","span":{"begin":387,"end":397},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1681","span":{"begin":412,"end":418},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T1682","span":{"begin":412,"end":418},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T1683","span":{"begin":412,"end":418},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T1684","span":{"begin":412,"end":418},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T1685","span":{"begin":515,"end":522},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T1686","span":{"begin":593,"end":599},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T1687","span":{"begin":593,"end":599},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T1688","span":{"begin":593,"end":599},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T1689","span":{"begin":593,"end":599},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T1690","span":{"begin":649,"end":657},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T95332","span":{"begin":5,"end":16},"obj":"Chemical"},{"id":"T87714","span":{"begin":75,"end":77},"obj":"Chemical"},{"id":"T87213","span":{"begin":218,"end":223},"obj":"Chemical"},{"id":"T91061","span":{"begin":225,"end":227},"obj":"Chemical"},{"id":"T43879","span":{"begin":263,"end":273},"obj":"Chemical"},{"id":"T514","span":{"begin":263,"end":269},"obj":"Chemical"},{"id":"T89299","span":{"begin":270,"end":273},"obj":"Chemical"},{"id":"T28627","span":{"begin":366,"end":368},"obj":"Chemical"},{"id":"T48164","span":{"begin":626,"end":636},"obj":"Chemical"},{"id":"T521","span":{"begin":626,"end":632},"obj":"Chemical"},{"id":"T84416","span":{"begin":633,"end":636},"obj":"Chemical"}],"attributes":[{"id":"A10037","pred":"chebi_id","subj":"T95332","obj":"http://purl.obolibrary.org/obo/CHEBI_78665"},{"id":"A78522","pred":"chebi_id","subj":"T87714","obj":"http://purl.obolibrary.org/obo/CHEBI_73505"},{"id":"A29948","pred":"chebi_id","subj":"T87213","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A64863","pred":"chebi_id","subj":"T91061","obj":"http://purl.obolibrary.org/obo/CHEBI_73462"},{"id":"A39045","pred":"chebi_id","subj":"T43879","obj":"http://purl.obolibrary.org/obo/CHEBI_15351"},{"id":"A71939","pred":"chebi_id","subj":"T43879","obj":"http://purl.obolibrary.org/obo/CHEBI_57288"},{"id":"A99997","pred":"chebi_id","subj":"T514","obj":"http://purl.obolibrary.org/obo/CHEBI_40574"},{"id":"A96523","pred":"chebi_id","subj":"T514","obj":"http://purl.obolibrary.org/obo/CHEBI_46887"},{"id":"A70932","pred":"chebi_id","subj":"T89299","obj":"http://purl.obolibrary.org/obo/CHEBI_15346"},{"id":"A85527","pred":"chebi_id","subj":"T89299","obj":"http://purl.obolibrary.org/obo/CHEBI_57287"},{"id":"A39478","pred":"chebi_id","subj":"T28627","obj":"http://purl.obolibrary.org/obo/CHEBI_73462"},{"id":"A4381","pred":"chebi_id","subj":"T48164","obj":"http://purl.obolibrary.org/obo/CHEBI_15351"},{"id":"A4073","pred":"chebi_id","subj":"T48164","obj":"http://purl.obolibrary.org/obo/CHEBI_57288"},{"id":"A45372","pred":"chebi_id","subj":"T521","obj":"http://purl.obolibrary.org/obo/CHEBI_40574"},{"id":"A4136","pred":"chebi_id","subj":"T521","obj":"http://purl.obolibrary.org/obo/CHEBI_46887"},{"id":"A46121","pred":"chebi_id","subj":"T84416","obj":"http://purl.obolibrary.org/obo/CHEBI_15346"},{"id":"A19059","pred":"chebi_id","subj":"T84416","obj":"http://purl.obolibrary.org/obo/CHEBI_57287"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T446","span":{"begin":254,"end":258},"obj":"http://purl.obolibrary.org/obo/GO_0050405"},{"id":"T447","span":{"begin":254,"end":258},"obj":"http://purl.obolibrary.org/obo/GO_0047322"},{"id":"T448","span":{"begin":254,"end":258},"obj":"http://purl.obolibrary.org/obo/GO_0004691"},{"id":"T449","span":{"begin":617,"end":621},"obj":"http://purl.obolibrary.org/obo/GO_0050405"},{"id":"T450","span":{"begin":617,"end":621},"obj":"http://purl.obolibrary.org/obo/GO_0047322"},{"id":"T451","span":{"begin":617,"end":621},"obj":"http://purl.obolibrary.org/obo/GO_0004691"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-sentences","denotations":[{"id":"T590","span":{"begin":0,"end":342},"obj":"Sentence"},{"id":"T591","span":{"begin":344,"end":665},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}

{"project":"LitCovid-PubTator","denotations":[{"id":"2803","span":{"begin":254,"end":258},"obj":"Gene"},{"id":"2804","span":{"begin":617,"end":621},"obj":"Gene"},{"id":"2888","span":{"begin":225,"end":227},"obj":"Gene"},{"id":"2920","span":{"begin":69,"end":73},"obj":"Species"},{"id":"2921","span":{"begin":126,"end":130},"obj":"Species"},{"id":"2922","span":{"begin":200,"end":204},"obj":"Species"},{"id":"2923","span":{"begin":536,"end":540},"obj":"Species"},{"id":"2993","span":{"begin":5,"end":16},"obj":"Chemical"},{"id":"2994","span":{"begin":218,"end":223},"obj":"Chemical"},{"id":"2995","span":{"begin":344,"end":355},"obj":"Chemical"},{"id":"2996","span":{"begin":555,"end":558},"obj":"Chemical"},{"id":"2997","span":{"begin":559,"end":570},"obj":"Chemical"}],"attributes":[{"id":"A2803","pred":"tao:has_database_id","subj":"2803","obj":"Gene:78975"},{"id":"A2804","pred":"tao:has_database_id","subj":"2804","obj":"Gene:78975"},{"id":"A2888","pred":"tao:has_database_id","subj":"2888","obj":"Gene:170587"},{"id":"A2920","pred":"tao:has_database_id","subj":"2920","obj":"Tax:10090"},{"id":"A2921","pred":"tao:has_database_id","subj":"2921","obj":"Tax:10116"},{"id":"A2922","pred":"tao:has_database_id","subj":"2922","obj":"Tax:10116"},{"id":"A2923","pred":"tao:has_database_id","subj":"2923","obj":"Tax:10090"},{"id":"A2993","pred":"tao:has_database_id","subj":"2993","obj":"MESH:C058787"},{"id":"A2994","pred":"tao:has_database_id","subj":"2994","obj":"MESH:D014867"},{"id":"A2995","pred":"tao:has_database_id","subj":"2995","obj":"MESH:C058787"},{"id":"A2997","pred":"tao:has_database_id","subj":"2997","obj":"MESH:C058787"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Oral royal jelly (1.0 mg/g body weight/d/3 weeks) 6–7 weeks old ICR mice EG: endurance exercise + royal jellyCG1: sedentary rats on royal jellyCG2: endurance exercise+ distilled waterCG3: sedentary rats on distilled water CS, β-HAD, and activities of AMPK and acetyl-CoA carboxylase in the soleus, plantaris, and tibialis anterior muscles. Royal jelly increased CS and β-HAD maximal activities in the soleus muscle compared with all CGs but failed to affect these enzymes in the plantaris and tibialis anterior muscles of sedentary mice compared with CG2.Royal jelly effects in the soleus muscle were mediated by AMPK and acetyl-CoA carboxylase activity. [106]"}