Oral 10-HDA (12-60 mg/kg body weight/d/4 months)  Obese old rats and stressed mice as models of sarcopenia and depression (male and female Sprague-Dawley and 2-months old male and female BALB/c)  EG1 and EG2: aged obese rats on 10-HDA (12 or 24 mg/kg/d for 3.5 months)EG3 and EG4: stressed BALB/c mice on 10-HDA (30 or 60 mg/kg/d for 4 months)CG1 and CG2: untreated aged obese rats and untreated stressed BALB/c mice  Body weight, weight of abdominal adipose tissue, and muscle mass.  10-HDA significantly increased weight gain and weight maintenance in aged rats/mice undergoing behavioral stress without any change in diet consumption. It also significantly decreased adipose tissue in female animals and increased muscle mass in male rodents compared with untreated controls.  [54]