Intragastric 10-HDA (1.6 mM/kg body weight) In vitroL6 myotubes obtained from Osaka biobankIn vivo7-weeks old male C57BL/6J mice In vitroEG: 10-HDACG1: AICAR (1 mM)CG2: DMSO (0.1%)In vivoEG: 10-HDA (1.6 mM)CG1: gum Arabic (5%) Glucose uptake, AMPK signaling, and Glut4 translocation. 10-HDA increased glucose uptake into L6 myotubes following AMPK activation and Glut4 translocation to the plasma membrane. AMPK activation was induced by the upstream kinase Ca²/calmodulin-dependent kinase β, independent of changes in AMP:ATP ratio and the liver kinase B1 pathway. [106]