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PMC:7601109 / 87158-89056 JSONTXT

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LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T166 1373-1378 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T769 161-167 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T770 268-276 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T771 502-510 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T772 863-869 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T773 896-902 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T774 935-941 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T775 1325-1329 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T776 1373-1378 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T777 1446-1465 Body_part denotes peripheral neuronal http://purl.org/sig/ont/fma/fma84664
T778 1576-1582 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T779 1645-1648 Body_part denotes gut http://purl.org/sig/ont/fma/fma7199
T780 1762-1768 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T781 1881-1887 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T145 691-703 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T146 1170-1182 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1518 67-77 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1519 152-167 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T1520 152-167 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T1521 152-167 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T1522 350-351 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1523 352-353 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1524 630-631 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1525 658-668 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1526 854-869 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T1527 854-869 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T1528 854-869 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T1529 896-902 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1530 896-902 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1531 896-902 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1532 896-902 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T1533 935-941 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1534 935-941 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1535 935-941 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1536 935-941 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T1537 1005-1011 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T1538 1315-1329 http://purl.obolibrary.org/obo/CL_0000514 denotes satellite cell
T1539 1373-1378 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1540 1373-1378 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1541 1417-1422 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T1542 1576-1582 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1543 1576-1582 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1544 1576-1582 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1545 1576-1582 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T1546 1645-1648 http://purl.obolibrary.org/obo/UBERON_0001007 denotes gut
T1547 1645-1648 http://purl.obolibrary.org/obo/UBERON_0001555 denotes gut
T1548 1645-1648 http://www.ebi.ac.uk/efo/EFO_0000834 denotes gut
T1549 1762-1768 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1550 1762-1768 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1551 1762-1768 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1552 1762-1768 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T1553 1812-1821 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T1554 1881-1887 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1555 1881-1887 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1556 1881-1887 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1557 1881-1887 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T53621 81-92 Chemical denotes royal jelly http://purl.obolibrary.org/obo/CHEBI_78665
T96470 256-267 Chemical denotes royal jelly http://purl.obolibrary.org/obo/CHEBI_78665
T436 268-276 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T99593 281-284 Chemical denotes HDA http://purl.obolibrary.org/obo/CHEBI_17314
T67564 295-302 Chemical denotes hydroxy http://purl.obolibrary.org/obo/CHEBI_43176
T34674 303-318 Chemical denotes 2-decenoic acid http://purl.obolibrary.org/obo/CHEBI_50465
T440 305-318 Chemical denotes decenoic acid http://purl.obolibrary.org/obo/CHEBI_36003
T59935 314-318 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T442 320-322 Chemical denotes GI http://purl.obolibrary.org/obo/CHEBI_73907
T11559 413-424 Chemical denotes royal jelly http://purl.obolibrary.org/obo/CHEBI_78665
T14279 502-510 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T445 512-523 Chemical denotes polyphenols http://purl.obolibrary.org/obo/CHEBI_26195
T87581 525-533 Chemical denotes vitamins http://purl.obolibrary.org/obo/CHEBI_33229
T3644 535-543 Chemical denotes minerals http://purl.obolibrary.org/obo/CHEBI_46662
T76986 549-563 Chemical denotes trace elements http://purl.obolibrary.org/obo/CHEBI_27027
T449 813-824 Chemical denotes royal jelly http://purl.obolibrary.org/obo/CHEBI_78665
T86989 1681-1689 Chemical denotes nutrient http://purl.obolibrary.org/obo/CHEBI_33284
T451 1799-1807 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T419 691-703 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T420 1170-1182 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T421 1256-1266 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T422 1466-1478 http://purl.obolibrary.org/obo/GO_0031099 denotes regeneration
T423 1812-1830 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T424 1812-1821 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T92 708-724 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T559 0-341 Sentence denotes Figure 1 Brief summary of the chemical composition and biological activities of royal jelly, bee pollen, and propolis along with their effects on aged skeletal muscle and possible underlying mechanism. ↑ denotes increase, ↓ denotes decrease, MRJPs: major royal jelly proteins, 10-HDA: trans-10-hydroxy-2-decenoic acid, GI: gastrointestinal.
T560 342-451 Sentence denotes Panels (A,B) describe the composition and the biological properties of royal jelly, bee pollen, and propolis.
T561 452-776 Sentence denotes Thanks to their rich structure (which consists of proteins, polyphenols, vitamins, minerals, and trace elements) [2,28,37,49,59,60,61,68,80,86], these bee substances demonstrate a wide range of therapeutic activities such as counteracting inflammation and oxidative stress, in addition to many others [37,38,39,43,45,63,83].
T562 777-870 Sentence denotes Panel (C) summarizes the effects of royal jelly, bee pollen, and propolis on skeletal muscle.
T563 871-1019 Sentence denotes These products increased muscle mass [36,54,95,96] and restored muscle function in old [36,38,95,96,97] and exhausted [54,90,101,106] animal models.
T564 1020-1485 Sentence denotes As shown in Panel (D), these effects originated from multiple molecular events that resulted in several therapeutic actions including amelioration of inflammation [36,38,90,101,107,108] and oxidative [95,106,109,110] damages, metabolic regulation [69,70,96,100,106,109,111,112], enhancements of satellite cell responsiveness [96,97], improving muscular blood supply [110], inhibition of catabolic genes [97], and promotion of peripheral neuronal regeneration [113].
T565 1486-1715 Sentence denotes However, future studies could examine the involvement of other possible mechanisms in the muscle-enhancing potential of these bee products such as the role of gut microbiome in the absorption of nutrient contents of bee products.
T566 1716-1898 Sentence denotes It is not clear if these api-materials affect muscle quality via modulation of sex steroids and signaling pathways of dietary restriction, which are known to affect muscle integrity.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2498 1645-1659 Species denotes gut microbiome Tax:749906
2499 286-318 Chemical denotes trans-10-hydroxy-2-decenoic acid
2500 512-523 Chemical denotes polyphenols MESH:D059808
2501 1799-1807 Chemical denotes steroids MESH:D013256
2502 691-703 Disease denotes inflammation MESH:D007249
2503 1170-1182 Disease denotes inflammation MESH:D007249