PMC:7601109 / 80364-82322
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T710 | 748-754 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T711 | 768-775 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T712 | 832-836 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T713 | 863-869 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T714 | 1057-1063 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T715 | 1064-1071 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T716 | 1096-1104 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T717 | 1135-1142 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T718 | 1158-1163 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
T719 | 1182-1188 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T720 | 1280-1287 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T721 | 1307-1313 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T722 | 1342-1349 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
T723 | 1494-1501 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T724 | 1521-1527 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T725 | 1748-1755 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
T726 | 1768-1789 | Body_part | denotes | skeletal muscle cells | http://purl.org/sig/ont/fma/fma9727 |
T727 | 1784-1789 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1424 | 325-327 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T1425 | 426-427 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T1426 | 729-735 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T1427 | 739-754 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
T1428 | 739-754 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
T1429 | 739-754 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1430 | 854-869 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
T1431 | 854-869 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
T1432 | 854-869 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1433 | 884-889 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | males |
T1434 | 884-889 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | males |
T1435 | 904-907 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | fat |
T1436 | 922-929 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | females |
T1437 | 1048-1063 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
T1438 | 1048-1063 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
T1439 | 1048-1063 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1440 | 1182-1188 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | muscle |
T1441 | 1182-1188 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | muscle |
T1442 | 1182-1188 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | muscle |
T1443 | 1182-1188 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | muscle |
T1444 | 1298-1313 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
T1445 | 1298-1313 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
T1446 | 1298-1313 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1447 | 1342-1349 | http://purl.obolibrary.org/obo/PR_000009054 | denotes | insulin |
T1448 | 1512-1527 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
T1449 | 1512-1527 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
T1450 | 1512-1527 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1451 | 1702-1711 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
T1452 | 1768-1789 | http://purl.obolibrary.org/obo/CL_0000188 | denotes | skeletal muscle cells |
T1453 | 1768-1783 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
T1454 | 1855-1863 | http://purl.obolibrary.org/obo/CL_0002372 | denotes | myotubes |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T77098 | 23-34 | Chemical | denotes | royal jelly | http://purl.obolibrary.org/obo/CHEBI_78665 |
T6628 | 165-170 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
T86300 | 285-296 | Chemical | denotes | royal jelly | http://purl.obolibrary.org/obo/CHEBI_78665 |
T77049 | 400-411 | Chemical | denotes | royal jelly | http://purl.obolibrary.org/obo/CHEBI_78665 |
T75059 | 434-439 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T85399 | 459-470 | Chemical | denotes | royal jelly | http://purl.obolibrary.org/obo/CHEBI_78665 |
T65480 | 505-508 | Chemical | denotes | HDA | http://purl.obolibrary.org/obo/CHEBI_17314 |
T89308 | 519-523 | Chemical | denotes | CAPE | http://purl.obolibrary.org/obo/CHEBI_8062 |
T68097 | 556-569 | Chemical | denotes | coumaric acid | http://purl.obolibrary.org/obo/CHEBI_23401 |
T83356 | 565-569 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T51798 | 571-582 | Chemical | denotes | kaempferide | http://purl.obolibrary.org/obo/CHEBI_58925|http://purl.obolibrary.org/obo/CHEBI_6099 |
T18820 | 599-603 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T34216 | 625-629 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T27834 | 661-670 | Chemical | denotes | auraptene | http://purl.obolibrary.org/obo/CHEBI_134355 |
T8702 | 680-683 | Chemical | denotes | HDA | http://purl.obolibrary.org/obo/CHEBI_17314 |
T23108 | 708-719 | Chemical | denotes | royal jelly | http://purl.obolibrary.org/obo/CHEBI_78665 |
T69523 | 768-775 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T14015 | 976-980 | Chemical | denotes | CAPE | http://purl.obolibrary.org/obo/CHEBI_8062 |
T73779 | 1064-1071 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T29149 | 1109-1112 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
T25600 | 1135-1142 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T53613 | 1158-1163 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
T31751 | 1272-1276 | Chemical | denotes | CAPE | http://purl.obolibrary.org/obo/CHEBI_8062 |
T66410 | 1280-1287 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T73100 | 1342-1349 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
T1240 | 1402-1412 | Chemical | denotes | flavonoids | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
T332 | 1431-1447 | Chemical | denotes | phenylpropanoids | http://purl.obolibrary.org/obo/CHEBI_26004 |
T94576 | 1494-1501 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T94354 | 1557-1568 | Chemical | denotes | kaempferide | http://purl.obolibrary.org/obo/CHEBI_58925|http://purl.obolibrary.org/obo/CHEBI_6099 |
T4848 | 1595-1599 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T65701 | 1605-1614 | Chemical | denotes | auraptene | http://purl.obolibrary.org/obo/CHEBI_134355 |
T51105 | 1638-1654 | Chemical | denotes | phenylpropanoids | http://purl.obolibrary.org/obo/CHEBI_26004 |
T91875 | 1678-1687 | Chemical | denotes | auraptene | http://purl.obolibrary.org/obo/CHEBI_134355 |
T76597 | 1748-1755 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
T8839 | 1879-1888 | Chemical | denotes | auraptene | http://purl.obolibrary.org/obo/CHEBI_134355 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T376 | 768-782 | http://purl.obolibrary.org/obo/GO_0046323 | denotes | glucose uptake |
T377 | 776-782 | http://purl.obolibrary.org/obo/GO_0098739 | denotes | uptake |
T378 | 776-782 | http://purl.obolibrary.org/obo/GO_0098657 | denotes | uptake |
T379 | 787-791 | http://purl.obolibrary.org/obo/GO_0050405 | denotes | AMPK |
T380 | 787-791 | http://purl.obolibrary.org/obo/GO_0047322 | denotes | AMPK |
T381 | 787-791 | http://purl.obolibrary.org/obo/GO_0004691 | denotes | AMPK |
T382 | 792-807 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T383 | 1064-1078 | http://purl.obolibrary.org/obo/GO_0046323 | denotes | glucose uptake |
T384 | 1072-1078 | http://purl.obolibrary.org/obo/GO_0098739 | denotes | uptake |
T385 | 1072-1078 | http://purl.obolibrary.org/obo/GO_0098657 | denotes | uptake |
T386 | 1189-1200 | http://purl.obolibrary.org/obo/GO_0006508 | denotes | proteolysis |
T387 | 1280-1294 | http://purl.obolibrary.org/obo/GO_0046323 | denotes | glucose uptake |
T388 | 1288-1294 | http://purl.obolibrary.org/obo/GO_0098739 | denotes | uptake |
T389 | 1288-1294 | http://purl.obolibrary.org/obo/GO_0098657 | denotes | uptake |
T390 | 1494-1508 | http://purl.obolibrary.org/obo/GO_0046323 | denotes | glucose uptake |
T391 | 1502-1508 | http://purl.obolibrary.org/obo/GO_0098739 | denotes | uptake |
T392 | 1502-1508 | http://purl.obolibrary.org/obo/GO_0098657 | denotes | uptake |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T471 | 0-71 | Sentence | denotes | In most studies, whole royal jelly, bee pollen, and propolis were used. |
T472 | 72-297 | Sentence | denotes | However, these products appeared in different forms e.g., neat vs processed bee pollen [90], water [109] vs ethanolic extracts [110] of propolis, lyophilized [98,99] and crude [97] vs enzyme-treated [59,95,96,97] royal jelly. |
T473 | 298-412 | Sentence | denotes | Both processed bee pollen [36] and pRJ [97,106] had better effects compared with crude bee pollen and royal jelly. |
T474 | 413-676 | Sentence | denotes | In addition, a large group of constituents of royal jelly and propolis were used such as 10-HDA [54,106], CAPE [69,101,102,103], artepillin C, coumaric acid, kaempferide [70], boropinic acid, 4-geranyloxyferulic acid, 7-isopentenyloxycoumarin, and auraptene [69]. |
T475 | 677-755 | Sentence | denotes | 10-HDA was the only element in royal jelly that was tested in skeletal muscle. |
T476 | 756-814 | Sentence | denotes | It enhanced glucose uptake via AMPK phosphorylation [106]. |
T477 | 815-975 | Sentence | denotes | It also restored body weight, restored skeletal muscle mass (only in males), and reduced fat mass (only in females) in aged rats undergoing chronic stress [54]. |
T478 | 976-1215 | Sentence | denotes | CAPE is one of the most investigated compounds in propolis: it enhanced skeletal muscle glucose uptake [111], inhibited cytokine and ROS production, prevented protein carbonylation, lipid peroxidation, and muscle proteolysis [101,102,103]. |
T479 | 1216-1363 | Sentence | denotes | The effects of whole ethanolic extracts of propolis and CAPE on glucose uptake in skeletal muscle were comparable to those of insulin [69,109,111]. |
T480 | 1364-1615 | Sentence | denotes | More, investigations of the effect of flavonoids and oxyprenylated phenylpropanoids abundant in ethanolic extracts of propolis on glucose uptake in skeletal muscle revealed superior effects of kaempferide [70], 4-geranyloxyferulic acid, and auraptene. |
T481 | 1616-1790 | Sentence | denotes | Among 5 oxyprenylated phenylpropanoids derived from propolis, auraptene most potently activated GLUT4 translocation and accelerated glucose influx into skeletal muscle cells. |
T482 | 1791-1958 | Sentence | denotes | Measurement of the incorporated amounts of these compounds into myotubes indicated that auraptene had the highest bioavailability among other effective compounds [69]. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1802 | 787-791 | Gene | denotes | AMPK | Gene:78975 |
1803 | 1342-1349 | Gene | denotes | insulin | Gene:3630 |
1804 | 1712-1717 | Gene | denotes | GLUT4 | Gene:25139 |
1805 | 904-907 | Gene | denotes | fat | Gene:83720 |
1806 | 939-943 | Species | denotes | rats | Tax:10116 |
1807 | 165-170 | Chemical | denotes | water | MESH:D014867 |
1808 | 519-523 | Chemical | denotes | CAPE | MESH:C055494 |
1809 | 542-554 | Chemical | denotes | artepillin C | MESH:C102259 |
1810 | 556-569 | Chemical | denotes | coumaric acid | MESH:D003373 |
1811 | 571-582 | Chemical | denotes | kaempferide | MESH:C449720 |
1812 | 589-603 | Chemical | denotes | boropinic acid | |
1813 | 605-629 | Chemical | denotes | 4-geranyloxyferulic acid | MESH:C552732 |
1814 | 631-655 | Chemical | denotes | 7-isopentenyloxycoumarin | MESH:C461443 |
1815 | 661-670 | Chemical | denotes | auraptene | MESH:C105832 |
1816 | 768-775 | Chemical | denotes | glucose | MESH:D005947 |
1817 | 976-980 | Chemical | denotes | CAPE | MESH:C055494 |
1818 | 1064-1071 | Chemical | denotes | glucose | MESH:D005947 |
1819 | 1109-1112 | Chemical | denotes | ROS | MESH:D017382 |
1820 | 1280-1287 | Chemical | denotes | glucose | MESH:D005947 |
1821 | 1402-1412 | Chemical | denotes | flavonoids | MESH:D005419 |
1822 | 1431-1447 | Chemical | denotes | phenylpropanoids | |
1823 | 1494-1501 | Chemical | denotes | glucose | MESH:D005947 |
1824 | 1557-1568 | Chemical | denotes | kaempferide | MESH:C449720 |
1825 | 1575-1599 | Chemical | denotes | 4-geranyloxyferulic acid | MESH:C552732 |
1826 | 1605-1614 | Chemical | denotes | auraptene | MESH:C105832 |
1827 | 1624-1637 | Chemical | denotes | oxyprenylated | |
1828 | 1638-1654 | Chemical | denotes | phenylpropanoids | |
1829 | 1678-1687 | Chemical | denotes | auraptene | MESH:C105832 |
1830 | 1748-1755 | Chemical | denotes | glucose | MESH:D005947 |
1831 | 1879-1888 | Chemical | denotes | auraptene | MESH:C105832 |