PMC:7601109 / 2926-3518 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7601109","sourcedb":"PMC","sourceid":"7601109","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7601109","text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers 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