PMC:7601109 / 2926-3518 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T84139","span":{"begin":105,"end":111},"obj":"Body_part"},{"id":"T62520","span":{"begin":164,"end":168},"obj":"Body_part"}],"attributes":[{"id":"A95712","pred":"fma_id","subj":"T84139","obj":"http://purl.org/sig/ont/fma/fma32558"},{"id":"A77297","pred":"fma_id","subj":"T62520","obj":"http://purl.org/sig/ont/fma/fma256135"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T17","span":{"begin":84,"end":94},"obj":"Disease"},{"id":"T18","span":{"begin":433,"end":457},"obj":"Disease"},{"id":"T19","span":{"begin":440,"end":448},"obj":"Disease"}],"attributes":[{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0006516"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0005148"},{"id":"A19","pred":"mondo_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T35774","span":{"begin":96,"end":111},"obj":"http://purl.obolibrary.org/obo/UBERON_0001134"},{"id":"T4366","span":{"begin":96,"end":111},"obj":"http://purl.obolibrary.org/obo/UBERON_0014892"},{"id":"T73667","span":{"begin":96,"end":111},"obj":"http://www.ebi.ac.uk/efo/EFO_0000888"},{"id":"T64354","span":{"begin":177,"end":178},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":332,"end":340},"obj":"Chemical"},{"id":"T13","span":{"begin":506,"end":508},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_26519"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T56212","span":{"begin":256,"end":261},"obj":"http://purl.obolibrary.org/obo/GO_0007568"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T6","span":{"begin":440,"end":457},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0000819"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T21","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"T22","span":{"begin":151,"end":294},"obj":"Sentence"},{"id":"T23","span":{"begin":295,"end":592},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"59","span":{"begin":393,"end":401},"obj":"Species"},{"id":"60","span":{"begin":84,"end":94},"obj":"Disease"},{"id":"61","span":{"begin":105,"end":125},"obj":"Disease"},{"id":"62","span":{"begin":407,"end":423},"obj":"Disease"},{"id":"63","span":{"begin":433,"end":457},"obj":"Disease"}],"attributes":[{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"Tax:9606"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D055948"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D018908"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:D002908"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"MESH:D003924"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"While the numbers of older adults are expanding all over the world, the pandemic of sarcopenia, skeletal muscle loss/weakness is also on the rise [1]. Loss of lean body mass is a direct effect of the inflammatory and oxidative conditions that develop with aging [1,2]—described as inflammaging. Both inflammatory mediators and free radicals, which are highly expressed in older seniors and in patients with chronic diseases, such as type 2 diabetes mellitus, cause remarkable shrinkage of fast-twitch type II fibers promoting their transformation into the slow-twitch type I fibers [1,3,4,5]."}