PMC:7600245 / 77146-78492
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T333 | 13-17 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T334 | 232-240 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
| T335 | 257-262 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T336 | 407-410 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T337 | 415-418 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T338 | 501-506 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T42 | 13-17 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T369 | 686-691 | Disease | denotes | polio | http://purl.obolibrary.org/obo/MONDO_0017373 |
| T370 | 699-713 | Disease | denotes | herpes simplex | http://purl.obolibrary.org/obo/MONDO_0004609 |
| T371 | 855-861 | Disease | denotes | dengue | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T372 | 1227-1235 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T791 | 32-33 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T792 | 364-365 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T793 | 390-398 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T794 | 419-426 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T795 | 481-488 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T796 | 492-506 | http://purl.obolibrary.org/obo/CL_0000010 | denotes | cultured cells |
| T797 | 692-697 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T798 | 714-719 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T799 | 745-750 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T800 | 770-775 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T801 | 862-867 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T802 | 959-964 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T803 | 1175-1176 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T804 | 1196-1197 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T805 | 1217-1223 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T806 | 1281-1287 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T403 | 19-28 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T87746 | 61-70 | Chemical | denotes | flavonoid | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
| T18882 | 94-105 | Chemical | denotes | resveratrol | http://purl.obolibrary.org/obo/CHEBI_27881 |
| T90539 | 107-116 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T82583 | 127-138 | Chemical | denotes | antioxidant | http://purl.obolibrary.org/obo/CHEBI_22586 |
| T48441 | 140-146 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T87394 | 208-217 | Chemical | denotes | Quercetin | http://purl.obolibrary.org/obo/CHEBI_16243 |
| T68803 | 257-262 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T25270 | 340-349 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T84764 | 380-389 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T35973 | 407-410 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T17050 | 441-450 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T91467 | 629-638 | Chemical | denotes | Quercetin | http://purl.obolibrary.org/obo/CHEBI_16243 |
| T69520 | 796-805 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T53088 | 881-890 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T15100 | 902-911 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T76164 | 1051-1061 | Chemical | denotes | flavonoids | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
| T89668 | 1103-1113 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T24478 | 1156-1165 | Chemical | denotes | quercetin | http://purl.obolibrary.org/obo/CHEBI_16243|http://purl.obolibrary.org/obo/CHEBI_57694 |
| T431 | 1293-1297 | Chemical | denotes | zinc | http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185 |
| T64235 | 1314-1323 | Chemical | denotes | vitamin C | http://purl.obolibrary.org/obo/CHEBI_21241 |
| T434 | 1314-1321 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T158 | 232-252 | http://purl.obolibrary.org/obo/GO_0070527 | denotes | platelet aggregation |
| T159 | 673-682 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T160 | 974-1004 | http://purl.obolibrary.org/obo/GO_1903901 | denotes | inhibits the viral replication |
| T161 | 987-1004 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T162 | 987-1004 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T606 | 0-82 | Sentence | denotes | On the other hand, quercetin is a natural penta-hydroxylated flavonoid (Figure 9). |
| T607 | 83-207 | Sentence | denotes | Similar to resveratrol, quercetin possesses antioxidant, oxygen scavenging, anti-inflammatory, and cardioprotective effects. |
| T608 | 208-326 | Sentence | denotes | Quercetin also inhibits platelet aggregation and lipid peroxidation and affects the function of several kinases [282]. |
| T609 | 327-427 | Sentence | denotes | Importantly, quercetin also exhibits a wide spectrum antiviral activity against DNA and RNA viruses. |
| T610 | 428-507 | Sentence | denotes | For example, quercetin inhibited several respiratory viruses in cultured cells. |
| T611 | 508-628 | Sentence | denotes | It also inhibited the cytopathic effects of rhinoviruses, echoviruses, coxsackieviruses, and polioviruses [283,284,285]. |
| T612 | 629-782 | Sentence | denotes | Quercetin also significantly reduced plaque formation by polio virus, herpes simplex virus 1, respiratory syncytial virus, and parainfluenza virus [286]. |
| T613 | 783-876 | Sentence | denotes | Furthermore, quercetin inhibited the replication of cytomegalovirus and dengue virus 2 [287]. |
| T614 | 877-1044 | Sentence | denotes | The antiviral effects of quercetin are thought to be because it either blocks the virus entry or inhibits the viral replication enzymes, i.e., viral polymerases [288]. |
| T615 | 1045-1128 | Sentence | denotes | Other flavonoids have recently been reported as potential inhibitors of Mpro [289]. |
| T616 | 1129-1263 | Sentence | denotes | Accordingly, the effect of quercetin alone as a prophylactic or as a treatment is being tested in COVID-19 patients (NCT04377789; 50). |
| T617 | 1264-1346 | Sentence | denotes | It is also being tested with zinc, bromelain, and vitamin C (NCT04468139; n = 60). |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2433 | 1117-1121 | Gene | denotes | Mpro | Gene:8673700 |
| 2434 | 699-721 | Species | denotes | herpes simplex virus 1 | Tax:10298 |
| 2435 | 723-750 | Species | denotes | respiratory syncytial virus | Tax:12814 |
| 2436 | 1236-1244 | Species | denotes | patients | Tax:9606 |
| 2437 | 469-480 | Species | denotes | respiratory | Tax:12814 |
| 2438 | 19-28 | Chemical | denotes | quercetin | MESH:D011794 |
| 2439 | 42-60 | Chemical | denotes | penta-hydroxylated | |
| 2440 | 61-70 | Chemical | denotes | flavonoid | MESH:D005419 |
| 2441 | 94-105 | Chemical | denotes | resveratrol | MESH:D000077185 |
| 2442 | 107-116 | Chemical | denotes | quercetin | MESH:D011794 |
| 2443 | 140-146 | Chemical | denotes | oxygen | MESH:D010100 |
| 2444 | 208-217 | Chemical | denotes | Quercetin | MESH:D011794 |
| 2445 | 257-262 | Chemical | denotes | lipid | MESH:D008055 |
| 2446 | 340-349 | Chemical | denotes | quercetin | MESH:D011794 |
| 2447 | 441-450 | Chemical | denotes | quercetin | MESH:D011794 |
| 2448 | 629-638 | Chemical | denotes | Quercetin | MESH:D011794 |
| 2449 | 796-805 | Chemical | denotes | quercetin | MESH:D011794 |
| 2450 | 902-911 | Chemical | denotes | quercetin | MESH:D011794 |
| 2451 | 1051-1061 | Chemical | denotes | flavonoids | MESH:D005419 |
| 2452 | 1156-1165 | Chemical | denotes | quercetin | MESH:D011794 |
| 2453 | 1314-1323 | Chemical | denotes | vitamin C | MESH:D001205 |
| 2454 | 232-252 | Disease | denotes | platelet aggregation | MESH:D001791 |
| 2455 | 1227-1235 | Disease | denotes | COVID-19 | MESH:C000657245 |