PMC:7600245 / 47806-48413 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T212","span":{"begin":13,"end":17},"obj":"Body_part"}],"attributes":[{"id":"A212","pred":"fma_id","subj":"T212","obj":"http://purl.org/sig/ont/fma/fma9712"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T16","span":{"begin":13,"end":17},"obj":"Body_part"}],"attributes":[{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T190","span":{"begin":262,"end":284},"obj":"Disease"},{"id":"T191","span":{"begin":273,"end":284},"obj":"Disease"},{"id":"T192","span":{"begin":286,"end":294},"obj":"Disease"},{"id":"T193","span":{"begin":296,"end":339},"obj":"Disease"},{"id":"T194","span":{"begin":310,"end":339},"obj":"Disease"},{"id":"T195","span":{"begin":330,"end":339},"obj":"Disease"},{"id":"T196","span":{"begin":341,"end":355},"obj":"Disease"},{"id":"T197","span":{"begin":357,"end":377},"obj":"Disease"},{"id":"T198","span":{"begin":368,"end":377},"obj":"Disease"},{"id":"T199","span":{"begin":379,"end":389},"obj":"Disease"},{"id":"T200","span":{"begin":414,"end":418},"obj":"Disease"},{"id":"T201","span":{"begin":504,"end":512},"obj":"Disease"}],"attributes":[{"id":"A190","pred":"mondo_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/MONDO_0005306"},{"id":"A191","pred":"mondo_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/MONDO_0003937"},{"id":"A192","pred":"mondo_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/MONDO_0002471"},{"id":"A193","pred":"mondo_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/MONDO_0018456"},{"id":"A194","pred":"mondo_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/MONDO_0011429"},{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0005578"},{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0005178"},{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0008383"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0005578"},{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0004857"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0005393"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T468","span":{"begin":79,"end":80},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T469","span":{"begin":212,"end":213},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T470","span":{"begin":379,"end":389},"obj":"http://www.ebi.ac.uk/cellline#tendon"},{"id":"T471","span":{"begin":379,"end":389},"obj":"http://www.ebi.ac.uk/efo/EFO_0000952"},{"id":"T472","span":{"begin":544,"end":545},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T473","span":{"begin":563,"end":568},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T686","span":{"begin":19,"end":27},"obj":"Chemical"},{"id":"T688","span":{"begin":56,"end":64},"obj":"Chemical"},{"id":"T689","span":{"begin":65,"end":70},"obj":"Chemical"},{"id":"T690","span":{"begin":97,"end":108},"obj":"Chemical"},{"id":"T691","span":{"begin":109,"end":120},"obj":"Chemical"},{"id":"T692","span":{"begin":116,"end":120},"obj":"Chemical"},{"id":"T693","span":{"begin":446,"end":454},"obj":"Chemical"},{"id":"T695","span":{"begin":563,"end":568},"obj":"Chemical"}],"attributes":[{"id":"A686","pred":"chebi_id","subj":"T686","obj":"http://purl.obolibrary.org/obo/CHEBI_59527"},{"id":"A687","pred":"chebi_id","subj":"T686","obj":"http://purl.obolibrary.org/obo/CHEBI_7476"},{"id":"A688","pred":"chebi_id","subj":"T688","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A689","pred":"chebi_id","subj":"T689","obj":"http://purl.obolibrary.org/obo/CHEBI_35475"},{"id":"A690","pred":"chebi_id","subj":"T690","obj":"http://purl.obolibrary.org/obo/CHEBI_16482"},{"id":"A691","pred":"chebi_id","subj":"T691","obj":"http://purl.obolibrary.org/obo/CHEBI_15366"},{"id":"A692","pred":"chebi_id","subj":"T692","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A693","pred":"chebi_id","subj":"T693","obj":"http://purl.obolibrary.org/obo/CHEBI_59527"},{"id":"A694","pred":"chebi_id","subj":"T693","obj":"http://purl.obolibrary.org/obo/CHEBI_7476"},{"id":"A695","pred":"chebi_id","subj":"T695","obj":"http://purl.obolibrary.org/obo/CHEBI_35209"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T39","span":{"begin":286,"end":294},"obj":"Phenotype"},{"id":"T40","span":{"begin":310,"end":339},"obj":"Phenotype"},{"id":"T41","span":{"begin":341,"end":355},"obj":"Phenotype"},{"id":"T42","span":{"begin":357,"end":377},"obj":"Phenotype"},{"id":"T43","span":{"begin":379,"end":389},"obj":"Phenotype"},{"id":"T44","span":{"begin":391,"end":403},"obj":"Phenotype"},{"id":"T45","span":{"begin":404,"end":408},"obj":"Phenotype"},{"id":"T46","span":{"begin":414,"end":418},"obj":"Phenotype"}],"attributes":[{"id":"A39","pred":"hp_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/HP_0025232"},{"id":"A40","pred":"hp_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/HP_0005681"},{"id":"A41","pred":"hp_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/HP_0002758"},{"id":"A42","pred":"hp_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/HP_0001370"},{"id":"A43","pred":"hp_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/HP_0025230"},{"id":"A44","pred":"hp_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/HP_0100607"},{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0012531"},{"id":"A46","pred":"hp_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/HP_0001997"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T357","span":{"begin":0,"end":132},"obj":"Sentence"},{"id":"T358","span":{"begin":133,"end":166},"obj":"Sentence"},{"id":"T359","span":{"begin":167,"end":429},"obj":"Sentence"},{"id":"T360","span":{"begin":430,"end":607},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1485","span":{"begin":513,"end":521},"obj":"Species"},{"id":"1486","span":{"begin":19,"end":27},"obj":"Chemical"},{"id":"1487","span":{"begin":95,"end":108},"obj":"Chemical"},{"id":"1488","span":{"begin":109,"end":120},"obj":"Chemical"},{"id":"1489","span":{"begin":446,"end":454},"obj":"Chemical"},{"id":"1490","span":{"begin":262,"end":284},"obj":"Disease"},{"id":"1491","span":{"begin":286,"end":294},"obj":"Disease"},{"id":"1492","span":{"begin":296,"end":339},"obj":"Disease"},{"id":"1493","span":{"begin":341,"end":355},"obj":"Disease"},{"id":"1494","span":{"begin":357,"end":377},"obj":"Disease"},{"id":"1495","span":{"begin":379,"end":389},"obj":"Disease"},{"id":"1496","span":{"begin":391,"end":408},"obj":"Disease"},{"id":"1497","span":{"begin":414,"end":418},"obj":"Disease"},{"id":"1498","span":{"begin":475,"end":489},"obj":"Disease"},{"id":"1499","span":{"begin":504,"end":512},"obj":"Disease"}],"attributes":[{"id":"A1485","pred":"tao:has_database_id","subj":"1485","obj":"Tax:9606"},{"id":"A1486","pred":"tao:has_database_id","subj":"1486","obj":"MESH:D009288"},{"id":"A1488","pred":"tao:has_database_id","subj":"1488","obj":"MESH:D019342"},{"id":"A1489","pred":"tao:has_database_id","subj":"1489","obj":"MESH:D009288"},{"id":"A1490","pred":"tao:has_database_id","subj":"1490","obj":"MESH:D013167"},{"id":"A1491","pred":"tao:has_database_id","subj":"1491","obj":"MESH:D002062"},{"id":"A1492","pred":"tao:has_database_id","subj":"1492","obj":"MESH:D001171"},{"id":"A1493","pred":"tao:has_database_id","subj":"1493","obj":"MESH:D010003"},{"id":"A1494","pred":"tao:has_database_id","subj":"1494","obj":"MESH:D001172"},{"id":"A1495","pred":"tao:has_database_id","subj":"1495","obj":"MESH:D052256"},{"id":"A1496","pred":"tao:has_database_id","subj":"1496","obj":"MESH:D004412"},{"id":"A1497","pred":"tao:has_database_id","subj":"1497","obj":"MESH:D006073"},{"id":"A1498","pred":"tao:has_database_id","subj":"1498","obj":"MESH:D016638"},{"id":"A1499","pred":"tao:has_database_id","subj":"1499","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In the other hand, naproxen is another synthetic, small molecule NSAID that is a derivative of 2-naphthalene-acetic acid (Figure 7). It was first approved by the U.S. FDA in 1976 for oral use in the treatment of a host of painful inflammatory conditions such as ankylosing spondylitis, bursitis, polyarticular juvenile idiopathic arthritis, osteoarthritis, rheumatoid arthritis, tendonitis, dysmenorrhea pain, and gout [148,149]. The efficacy of naproxen in the treatment of critically ill, hospitalized COVID-19 patients is being evaluated in a randomized, open label clinical trial (NCT04325633; n = 584)."}