PMC:7594251 / 79396-80403
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T151 | 80-88 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T152 | 768-776 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T74 | 557-564 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T75 | 628-635 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T559 | 57-66 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
| T560 | 71-79 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T561 | 190-198 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T562 | 244-245 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T96610 | 268-270 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T564 | 713-714 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T565 | 781-789 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T566 | 859-860 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T567 | 954-955 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T568 | 990-991 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T6388 | 80-88 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T89619 | 151-158 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T8279 | 268-270 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T37445 | 396-403 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T13543 | 468-472 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T67042 | 602-613 | Chemical | denotes | polypeptide | http://purl.obolibrary.org/obo/CHEBI_15841 |
| T90729 | 715-719 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T47940 | 768-776 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T337 | 781-789 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T60143 | 861-878 | Chemical | denotes | chemical compound | http://purl.obolibrary.org/obo/CHEBI_37577 |
| T22513 | 956-960 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T521 | 0-89 | Sentence | denotes | As mentioned before, ssNMR can provide information about membranes and membrane proteins. |
| T522 | 90-522 | Sentence | denotes | For this reason, ssNMR can be used to detect interactions of ligands with receptors embedded to the membrane which enables the mapping of binding site of a receptor by utilizing CP-MAS (cross-polarization magic-angle spinning) NMR and site specific mutagenesis [355]. ssNMR can provide the conformation of ligands bound to the receptor which can then be used to optimize future drug in terms of better affinity and efficiency [355]. |
| T523 | 523-680 | Sentence | denotes | Since ssNMR is also applicable to amyloid research, it can be used for probing polypeptide structures of amyloid and intermolecular contacts between fibrils. |
| T524 | 681-796 | Sentence | denotes | The potential is for the design a drug that will inhibit the process of aggregation of proteins and peptides [355]. |
| T525 | 797-1007 | Sentence | denotes | Lastly, since ssNMR gains insight into physical properties of a chemical compound it can be used for control of the process of formulation and processing of a drug to help assess the purity of a compound [358]. |