PMC:7594251 / 53785-54153 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T64359","span":{"begin":210,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A37971","pred":"fma_id","subj":"T64359","obj":"http://purl.org/sig/ont/fma/fma67906"}],"text":"It is worthwhile to mention that ligands that are in fast exchange between the bound and the free form (dissociation constants ranging from μM to mM) get enough bound time to transfer the negative NOE from the protein complex to the population of the free molecules, yet usually retain the chemical shift of the free molecule along with the relaxation characteristics."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T378","span":{"begin":210,"end":225},"obj":"http://purl.obolibrary.org/obo/GO_0043234"}],"text":"It is worthwhile to mention that ligands that are in fast exchange between the bound and the free form (dissociation constants ranging from μM to mM) get enough bound time to transfer the negative NOE from the protein complex to the population of the free molecules, yet usually retain the chemical shift of the free molecule along with the relaxation characteristics."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19755","span":{"begin":33,"end":40},"obj":"Chemical"},{"id":"T20113","span":{"begin":210,"end":217},"obj":"Chemical"},{"id":"T44996","span":{"begin":256,"end":265},"obj":"Chemical"},{"id":"T20150","span":{"begin":317,"end":325},"obj":"Chemical"}],"attributes":[{"id":"A6970","pred":"chebi_id","subj":"T19755","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A24752","pred":"chebi_id","subj":"T20113","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A69039","pred":"chebi_id","subj":"T44996","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A87166","pred":"chebi_id","subj":"T20150","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"It is worthwhile to mention that ligands that are in fast exchange between the bound and the free form (dissociation constants ranging from μM to mM) get enough bound time to transfer the negative NOE from the protein complex to the population of the free molecules, yet usually retain the chemical shift of the free molecule along with the relaxation characteristics."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T89047","span":{"begin":58,"end":66},"obj":"http://purl.obolibrary.org/obo/GO_0015297"}],"text":"It is worthwhile to mention that ligands that are in fast exchange between the bound and the free form (dissociation constants ranging from μM to mM) get enough bound time to transfer the negative NOE from the protein complex to the population of the free molecules, yet usually retain the chemical shift of the free molecule along with the relaxation characteristics."}

{"project":"LitCovid-sentences","denotations":[{"id":"T372","span":{"begin":0,"end":368},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"It is worthwhile to mention that ligands that are in fast exchange between the bound and the free form (dissociation constants ranging from μM to mM) get enough bound time to transfer the negative NOE from the protein complex to the population of the free molecules, yet usually retain the chemical shift of the free molecule along with the relaxation characteristics."}