6. Conclusions NMR has become a “gold standard” method in drug design due to its speed, simplicity, and reproducibility. The standardized ppm scale allows one to compare all NMR results and gather them in databases for the common use of researchers. Although sample labeling was limiting in the beginning, it has now become a strength of NMR that permits the observation of big molecules and/or biomolecular processes “through the door lock”. NMR is the only analytical technique that permits qualitative and quantitative analysis without previous sample purification or separation. High precision NMR data still requires long experiment times and has elevated costs; however, these will no doubt be alleviated in the future.