PMC:7589163 / 47917-49016
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T223","span":{"begin":8,"end":19},"obj":"Body_part"},{"id":"T224","span":{"begin":48,"end":52},"obj":"Body_part"},{"id":"T225","span":{"begin":74,"end":87},"obj":"Body_part"},{"id":"T226","span":{"begin":116,"end":130},"obj":"Body_part"},{"id":"T227","span":{"begin":116,"end":120},"obj":"Body_part"},{"id":"T228","span":{"begin":173,"end":177},"obj":"Body_part"},{"id":"T229","span":{"begin":294,"end":311},"obj":"Body_part"},{"id":"T230","span":{"begin":827,"end":837},"obj":"Body_part"},{"id":"T231","span":{"begin":972,"end":976},"obj":"Body_part"}],"attributes":[{"id":"A223","pred":"fma_id","subj":"T223","obj":"http://purl.org/sig/ont/fma/fma82738"},{"id":"A224","pred":"fma_id","subj":"T224","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A225","pred":"fma_id","subj":"T225","obj":"http://purl.org/sig/ont/fma/fma82779"},{"id":"A226","pred":"fma_id","subj":"T226","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A227","pred":"fma_id","subj":"T227","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A228","pred":"fma_id","subj":"T228","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A229","pred":"fma_id","subj":"T229","obj":"http://purl.org/sig/ont/fma/fma9668"},{"id":"A230","pred":"fma_id","subj":"T230","obj":"http://purl.org/sig/ont/fma/fma82738"},{"id":"A231","pred":"fma_id","subj":"T231","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T85","span":{"begin":294,"end":311},"obj":"Body_part"}],"attributes":[{"id":"A85","pred":"uberon_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/UBERON_0000949"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T185","span":{"begin":536,"end":548},"obj":"Disease"},{"id":"T186","span":{"begin":1080,"end":1092},"obj":"Disease"}],"attributes":[{"id":"A185","pred":"mondo_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A186","pred":"mondo_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T485","span":{"begin":116,"end":120},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T486","span":{"begin":121,"end":130},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T487","span":{"begin":294,"end":311},"obj":"http://purl.obolibrary.org/obo/UBERON_0000949"},{"id":"T488","span":{"begin":294,"end":311},"obj":"http://www.ebi.ac.uk/efo/EFO_0002969"},{"id":"T489","span":{"begin":972,"end":976},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T490","span":{"begin":1034,"end":1035},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T715","span":{"begin":8,"end":19},"obj":"Chemical"},{"id":"T716","span":{"begin":14,"end":19},"obj":"Chemical"},{"id":"T717","span":{"begin":74,"end":87},"obj":"Chemical"},{"id":"T718","span":{"begin":199,"end":210},"obj":"Chemical"},{"id":"T719","span":{"begin":294,"end":303},"obj":"Chemical"},{"id":"T720","span":{"begin":352,"end":363},"obj":"Chemical"},{"id":"T721","span":{"begin":414,"end":419},"obj":"Chemical"},{"id":"T722","span":{"begin":477,"end":486},"obj":"Chemical"},{"id":"T723","span":{"begin":556,"end":591},"obj":"Chemical"},{"id":"T724","span":{"begin":593,"end":597},"obj":"Chemical"},{"id":"T725","span":{"begin":616,"end":625},"obj":"Chemical"},{"id":"T726","span":{"begin":644,"end":668},"obj":"Chemical"},{"id":"T727","span":{"begin":750,"end":763},"obj":"Chemical"},{"id":"T728","span":{"begin":801,"end":805},"obj":"Chemical"},{"id":"T729","span":{"begin":819,"end":837},"obj":"Chemical"},{"id":"T730","span":{"begin":827,"end":837},"obj":"Chemical"},{"id":"T731","span":{"begin":833,"end":837},"obj":"Chemical"},{"id":"T732","span":{"begin":839,"end":842},"obj":"Chemical"},{"id":"T733","span":{"begin":847,"end":850},"obj":"Chemical"},{"id":"T737","span":{"begin":870,"end":879},"obj":"Chemical"}],"attributes":[{"id":"A715","pred":"chebi_id","subj":"T715","obj":"http://purl.obolibrary.org/obo/CHEBI_35366"},{"id":"A716","pred":"chebi_id","subj":"T716","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A717","pred":"chebi_id","subj":"T717","obj":"http://purl.obolibrary.org/obo/CHEBI_16247"},{"id":"A718","pred":"chebi_id","subj":"T718","obj":"http://purl.obolibrary.org/obo/CHEBI_23899"},{"id":"A719","pred":"chebi_id","subj":"T719","obj":"http://purl.obolibrary.org/obo/CHEBI_24621"},{"id":"A720","pred":"chebi_id","subj":"T720","obj":"http://purl.obolibrary.org/obo/CHEBI_25212"},{"id":"A721","pred":"chebi_id","subj":"T721","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A722","pred":"chebi_id","subj":"T722","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A723","pred":"chebi_id","subj":"T723","obj":"http://purl.obolibrary.org/obo/CHEBI_140399"},{"id":"A724","pred":"chebi_id","subj":"T724","obj":"http://purl.obolibrary.org/obo/CHEBI_140399"},{"id":"A725","pred":"chebi_id","subj":"T725","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A726","pred":"chebi_id","subj":"T726","obj":"http://purl.obolibrary.org/obo/CHEBI_35705"},{"id":"A727","pred":"chebi_id","subj":"T727","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"},{"id":"A728","pred":"chebi_id","subj":"T728","obj":"http://purl.obolibrary.org/obo/CHEBI_140399"},{"id":"A729","pred":"chebi_id","subj":"T729","obj":"http://purl.obolibrary.org/obo/CHEBI_25681"},{"id":"A730","pred":"chebi_id","subj":"T730","obj":"http://purl.obolibrary.org/obo/CHEBI_35366"},{"id":"A731","pred":"chebi_id","subj":"T731","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A732","pred":"chebi_id","subj":"T732","obj":"http://purl.obolibrary.org/obo/CHEBI_28364"},{"id":"A733","pred":"chebi_id","subj":"T733","obj":"http://purl.obolibrary.org/obo/CHEBI_16016"},{"id":"A734","pred":"chebi_id","subj":"T733","obj":"http://purl.obolibrary.org/obo/CHEBI_28125"},{"id":"A735","pred":"chebi_id","subj":"T733","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A736","pred":"chebi_id","subj":"T733","obj":"http://purl.obolibrary.org/obo/CHEBI_36005"},{"id":"A737","pred":"chebi_id","subj":"T737","obj":"http://purl.obolibrary.org/obo/CHEBI_132120"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T119","span":{"begin":536,"end":548},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T120","span":{"begin":700,"end":721},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T121","span":{"begin":1080,"end":1092},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T289","span":{"begin":0,"end":131},"obj":"Sentence"},{"id":"T290","span":{"begin":132,"end":318},"obj":"Sentence"},{"id":"T291","span":{"begin":319,"end":413},"obj":"Sentence"},{"id":"T292","span":{"begin":414,"end":609},"obj":"Sentence"},{"id":"T293","span":{"begin":610,"end":800},"obj":"Sentence"},{"id":"T294","span":{"begin":801,"end":906},"obj":"Sentence"},{"id":"T295","span":{"begin":907,"end":1099},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"1233","span":{"begin":0,"end":19},"obj":"Chemical"},{"id":"1234","span":{"begin":74,"end":87},"obj":"Chemical"},{"id":"1235","span":{"begin":199,"end":210},"obj":"Chemical"},{"id":"1236","span":{"begin":324,"end":331},"obj":"Chemical"},{"id":"1237","span":{"begin":336,"end":351},"obj":"Chemical"},{"id":"1238","span":{"begin":819,"end":837},"obj":"Chemical"},{"id":"1239","span":{"begin":847,"end":850},"obj":"Chemical"},{"id":"1240","span":{"begin":536,"end":548},"obj":"Disease"},{"id":"1241","span":{"begin":1080,"end":1092},"obj":"Disease"}],"attributes":[{"id":"A1233","pred":"tao:has_database_id","subj":"1233","obj":"MESH:D015525"},{"id":"A1234","pred":"tao:has_database_id","subj":"1234","obj":"MESH:D010743"},{"id":"A1235","pred":"tao:has_database_id","subj":"1235","obj":"MESH:D015777"},{"id":"A1238","pred":"tao:has_database_id","subj":"1238","obj":"MESH:D015525"},{"id":"A1239","pred":"tao:has_database_id","subj":"1239","obj":"MESH:C027493"},{"id":"A1240","pred":"tao:has_database_id","subj":"1240","obj":"MESH:D007249"},{"id":"A1241","pred":"tao:has_database_id","subj":"1241","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes. Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189]. Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193]. PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195]. These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196]. SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins. These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197]."}