PMC:7572937 / 3662-4746
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7572937","sourcedb":"PMC","sourceid":"7572937","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7572937","text":"Our body maintains its homeostasis and protection from the external environment via different types of barriers. Skin and mucosal surfaces are the barriers separating the inside from the outside of the body3. The mucosal surfaces include the gastrointestinal (GI) tract, the respiratory tract, the oral cavity, the urogenital tract, and the eye. Tremendous amounts of commensal bacteria and pathogens exist in mucosal surfaces, and they come in direct contact with the harsh external environment4. To defend our body against external attacks, many immune cells are required in the surface region. As a result, in healthy adults, approximately 80% of immune cells are in the mucosal system5. Immune responses need to be restricted and regulated at the necessary sites to maintain homeostasis. Immune cells cooperate with other epithelial cells and stromal cells and compose an independent mucosal immune system. The mucosal immune system includes epithelial cells, macrophages, monocytes, neutrophils, B and T cells, innate lymphoid cells, dendritic cells, and natural killer cells3,6.","tracks":[{"project":"MyTest","denotations":[{"id":"33082511-26174765-29997538","span":{"begin":206,"end":207},"obj":"26174765"},{"id":"33082511-27317359-29997539","span":{"begin":495,"end":496},"obj":"27317359"},{"id":"33082511-26174765-29997540","span":{"begin":1080,"end":1081},"obj":"26174765"},{"id":"33082511-19855405-29997541","span":{"begin":1082,"end":1083},"obj":"19855405"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"33082511-26174765-29997538","pred":"source","obj":"MyTest"},{"subj":"33082511-27317359-29997539","pred":"source","obj":"MyTest"},{"subj":"33082511-26174765-29997540","pred":"source","obj":"MyTest"},{"subj":"33082511-19855405-29997541","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"33082511-26174765-29997538","span":{"begin":206,"end":207},"obj":"26174765"},{"id":"33082511-27317359-29997539","span":{"begin":495,"end":496},"obj":"27317359"},{"id":"33082511-26174765-29997540","span":{"begin":1080,"end":1081},"obj":"26174765"},{"id":"33082511-19855405-29997541","span":{"begin":1082,"end":1083},"obj":"19855405"}],"attributes":[{"subj":"33082511-26174765-29997538","pred":"source","obj":"2_test"},{"subj":"33082511-27317359-29997539","pred":"source","obj":"2_test"},{"subj":"33082511-26174765-29997540","pred":"source","obj":"2_test"},{"subj":"33082511-19855405-29997541","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"MyTest","color":"#93ecda","default":true},{"id":"2_test","color":"#ecc093"}]}]}}