> top > docs > PMC:7571312 > spans > 58168-59224 > annotations

PMC:7571312 / 58168-59224 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T493 250-251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T494 900-902 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T495 937-942 http://purl.obolibrary.org/obo/CLO_0007706 denotes M + H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T351 72-79 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T35648 80-93 Chemical denotes 1H-indol-2-yl http://purl.obolibrary.org/obo/CHEBI_51611
T14380 80-82 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T47527 94-102 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T17117 106-112 Chemical denotes leucyl http://purl.obolibrary.org/obo/CHEBI_32630|http://purl.obolibrary.org/obo/CHEBI_37904
T89113 113-118 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T12500 122-125 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T40611 155-168 Chemical denotes butyl acetate http://purl.obolibrary.org/obo/CHEBI_31328
T53583 155-160 Chemical denotes butyl http://purl.obolibrary.org/obo/CHEBI_41264
T85901 161-168 Chemical denotes acetate http://purl.obolibrary.org/obo/CHEBI_30089|http://purl.obolibrary.org/obo/CHEBI_47622
T87477 186-206 Chemical denotes 4-chlorobenzoic acid http://purl.obolibrary.org/obo/CHEBI_30747
T31167 188-206 Chemical denotes chlorobenzoic acid http://purl.obolibrary.org/obo/CHEBI_23134|http://purl.obolibrary.org/obo/CHEBI_51967
T53497 202-206 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T3423 326-334 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T369 335-350 Chemical denotes dichloromethane http://purl.obolibrary.org/obo/CHEBI_15767
T64316 398-400 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T371 415-419 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T372 448-450 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T9840 474-476 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T53167 500-502 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T48220 540-542 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T80277 592-594 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T57111 618-620 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T378 644-646 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T68385 670-672 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T89225 696-698 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T381 715-717 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T42226 786-788 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T383 805-807 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T62942 824-826 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T385 900-902 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T5217 980-983 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T387 989-992 Chemical denotes DCM http://purl.obolibrary.org/obo/CHEBI_15767

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T372 0-266 Sentence denotes Following the procedure described for the preparation of (3S)-3-({N-[(4-methoxy-1H-indol-2-yl)carbonyl]-l-leucyl}amino)-2-oxo-4-[(3S)-2-oxopyrrolidin-3-yl]butyl acetate but substituting 4-chlorobenzoic acid and making noncritical variations provided a crude product.
T373 267-397 Sentence denotes This material was purified by Biotage MPLC (25 M, 2.5–4.5% methanol/dichloromethane) to afford 172 mg (80%) of the title compound.
T374 398-945 Sentence denotes 1H NMR (400 MHz, DMSO-d6) δ 11.58 (d, J = 1.8 Hz, 1H), 8.63 (d, J = 7.8 Hz, 1H), 8.46 (d, J = 7.6 Hz, 1H), 7.98 (d, J = 8.6 Hz, 2H), 7.65 (s, 1H), 7.62 (d, J = 8.6 Hz, 2H), 7.37 (d, J = 1.8 Hz, 1H), 7.08 (t, J = 8.0 Hz, 1H), 6.99 (d, J = 8.3 Hz, 1H), 6.50 (d, J = 7.6 Hz, 1H), 5.13 (d, J = 1.5 Hz, 1H), 5.07–5.23 (m, 1H), 4.44–4.52 (m, 2H), 3.87 (s, 3H), 3.04–3.14 (m, 2H), 2.28–2.38 (m, 1H), 2.06–2.26 (m, 1H), 1.97–2.06 (m, 1H), 1.51–1.78 (m, 5H), 0.94 (d, J = 6.3 Hz, 3H), 0.89 (d, J = 6.3 Hz, 3H); MS (ESI+) for C31H35ClN4O7m/z 611.1 (M + H)+.
T375 946-1021 Sentence denotes Anal. calcd for C31H35ClN4O7·0.72 H2O·0.05 DCM: C, 59.36; H, 5.86; N, 8.92.
T376 1022-1056 Sentence denotes Found: C, 59.31; H, 5.99; N, 9.23.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T10 989-992 Phenotype denotes DCM http://purl.obolibrary.org/obo/HP_0001644

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1296 186-206 Chemical denotes 4-chlorobenzoic acid MESH:C040768
1297 326-334 Chemical denotes methanol MESH:D000432
1298 335-350 Chemical denotes dichloromethane MESH:D008752
1299 962-974 Chemical denotes C31H35ClN4O7
1300 980-983 Chemical denotes H2O
1301 989-992 Chemical denotes DCM MESH:D008752
1302 994-995 Chemical denotes C MESH:D002244
1303 1013-1014 Chemical denotes N MESH:D009584
1304 1029-1030 Chemical denotes C MESH:D002244
1305 1048-1049 Chemical denotes N MESH:D009584