PMC:7571312 / 40222-40535 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T90","span":{"begin":67,"end":76},"obj":"Body_part"}],"attributes":[{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma82749"}],"text":"ith methyl N-(tert-butoxycarbonyl)-3-[(3S)-2-oxopyrrolidin-3-yl]-l-alaninate (10 g, 35 mmol), THF (200 mL), and chloroiodomethane (10.2 mL, 140 mmol), and the solution was cooled to −77 °C. LDA (140 mL, 210 mmol, 1.5 M mono-THF complex in cyclohexane) was added via a pressure-equalizing dropping funnel at such a"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T403","span":{"begin":81,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0003431"},{"id":"T404","span":{"begin":266,"end":267},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T405","span":{"begin":312,"end":313},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"ith methyl N-(tert-butoxycarbonyl)-3-[(3S)-2-oxopyrrolidin-3-yl]-l-alaninate (10 g, 35 mmol), THF (200 mL), and chloroiodomethane (10.2 mL, 140 mmol), and the solution was cooled to −77 °C. LDA (140 mL, 210 mmol, 1.5 M mono-THF complex in cyclohexane) was added via a pressure-equalizing dropping funnel at such a"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T665","span":{"begin":4,"end":10},"obj":"Chemical"},{"id":"T667","span":{"begin":14,"end":33},"obj":"Chemical"},{"id":"T668","span":{"begin":67,"end":76},"obj":"Chemical"},{"id":"T669","span":{"begin":94,"end":97},"obj":"Chemical"},{"id":"T672","span":{"begin":159,"end":167},"obj":"Chemical"},{"id":"T673","span":{"begin":224,"end":227},"obj":"Chemical"},{"id":"T676","span":{"begin":239,"end":250},"obj":"Chemical"}],"attributes":[{"id":"A665","pred":"chebi_id","subj":"T665","obj":"http://purl.obolibrary.org/obo/CHEBI_32875"},{"id":"A666","pred":"chebi_id","subj":"T665","obj":"http://purl.obolibrary.org/obo/CHEBI_29309"},{"id":"A667","pred":"chebi_id","subj":"T667","obj":"http://purl.obolibrary.org/obo/CHEBI_48502"},{"id":"A668","pred":"chebi_id","subj":"T668","obj":"http://purl.obolibrary.org/obo/CHEBI_32439"},{"id":"A669","pred":"chebi_id","subj":"T669","obj":"http://purl.obolibrary.org/obo/CHEBI_15635"},{"id":"A670","pred":"chebi_id","subj":"T669","obj":"http://purl.obolibrary.org/obo/CHEBI_20506"},{"id":"A671","pred":"chebi_id","subj":"T669","obj":"http://purl.obolibrary.org/obo/CHEBI_26911"},{"id":"A672","pred":"chebi_id","subj":"T672","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A673","pred":"chebi_id","subj":"T673","obj":"http://purl.obolibrary.org/obo/CHEBI_15635"},{"id":"A674","pred":"chebi_id","subj":"T673","obj":"http://purl.obolibrary.org/obo/CHEBI_20506"},{"id":"A675","pred":"chebi_id","subj":"T673","obj":"http://purl.obolibrary.org/obo/CHEBI_26911"},{"id":"A676","pred":"chebi_id","subj":"T676","obj":"http://purl.obolibrary.org/obo/CHEBI_29005"}],"text":"ith methyl N-(tert-butoxycarbonyl)-3-[(3S)-2-oxopyrrolidin-3-yl]-l-alaninate (10 g, 35 mmol), THF (200 mL), and chloroiodomethane (10.2 mL, 140 mmol), and the solution was cooled to −77 °C. LDA (140 mL, 210 mmol, 1.5 M mono-THF complex in cyclohexane) was added via a pressure-equalizing dropping funnel at such a"}