PMC:7571312 / 12753-13040 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T58451","span":{"begin":245,"end":248},"obj":"Body_part"}],"attributes":[{"id":"A85147","pred":"fma_id","subj":"T58451","obj":"http://purl.org/sig/ont/fma/fma20935"}],"text":"Scheme 2 Preparation of Substituted Acyloxymethylketones and Aminomethylketones\n(i) Boc-Leu-OH, HATU, NMM, N,N-dimethylformamide (DMF), 0 °C (64%), (ii) 4 M HCl/dioxane, (iii) HATU, 4-MeO-2-indolecarboxylic acid, NMM, DMF, 0 °C (61%), and (iv) CsF, DMF, carboxylic acid, 60 °C (43–91%)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T184","span":{"begin":85,"end":88},"obj":"Chemical"},{"id":"T185","span":{"begin":89,"end":92},"obj":"Chemical"},{"id":"T188","span":{"begin":108,"end":129},"obj":"Chemical"},{"id":"T189","span":{"begin":131,"end":134},"obj":"Chemical"},{"id":"T190","span":{"begin":158,"end":161},"obj":"Chemical"},{"id":"T191","span":{"begin":162,"end":169},"obj":"Chemical"},{"id":"T192","span":{"begin":191,"end":212},"obj":"Chemical"},{"id":"T193","span":{"begin":208,"end":212},"obj":"Chemical"},{"id":"T194","span":{"begin":219,"end":222},"obj":"Chemical"},{"id":"T195","span":{"begin":250,"end":253},"obj":"Chemical"},{"id":"T196","span":{"begin":255,"end":270},"obj":"Chemical"},{"id":"T197","span":{"begin":266,"end":270},"obj":"Chemical"}],"attributes":[{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_48502"},{"id":"A185","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_15603"},{"id":"A186","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_25017"},{"id":"A187","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_30006"},{"id":"A188","pred":"chebi_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A189","pred":"chebi_id","subj":"T189","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A190","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_17883"},{"id":"A191","pred":"chebi_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/CHEBI_46923"},{"id":"A192","pred":"chebi_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/CHEBI_38610"},{"id":"A193","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A194","pred":"chebi_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A195","pred":"chebi_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A196","pred":"chebi_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/CHEBI_33575"},{"id":"A197","pred":"chebi_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"Scheme 2 Preparation of Substituted Acyloxymethylketones and Aminomethylketones\n(i) Boc-Leu-OH, HATU, NMM, N,N-dimethylformamide (DMF), 0 °C (64%), (ii) 4 M HCl/dioxane, (iii) HATU, 4-MeO-2-indolecarboxylic acid, NMM, DMF, 0 °C (61%), and (iv) CsF, DMF, carboxylic acid, 60 °C (43–91%)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T66","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T67","span":{"begin":81,"end":287},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Scheme 2 Preparation of Substituted Acyloxymethylketones and Aminomethylketones\n(i) Boc-Leu-OH, HATU, NMM, N,N-dimethylformamide (DMF), 0 °C (64%), (ii) 4 M HCl/dioxane, (iii) HATU, 4-MeO-2-indolecarboxylic acid, NMM, DMF, 0 °C (61%), and (iv) CsF, DMF, carboxylic acid, 60 °C (43–91%)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"316","span":{"begin":37,"end":57},"obj":"Chemical"},{"id":"317","span":{"begin":62,"end":80},"obj":"Chemical"},{"id":"331","span":{"begin":85,"end":88},"obj":"Gene"},{"id":"332","span":{"begin":97,"end":101},"obj":"Chemical"},{"id":"333","span":{"begin":103,"end":106},"obj":"Chemical"},{"id":"334","span":{"begin":108,"end":129},"obj":"Chemical"},{"id":"335","span":{"begin":131,"end":134},"obj":"Chemical"},{"id":"336","span":{"begin":158,"end":161},"obj":"Chemical"},{"id":"337","span":{"begin":162,"end":169},"obj":"Chemical"},{"id":"338","span":{"begin":177,"end":181},"obj":"Chemical"},{"id":"339","span":{"begin":183,"end":212},"obj":"Chemical"},{"id":"340","span":{"begin":214,"end":217},"obj":"Chemical"},{"id":"341","span":{"begin":219,"end":222},"obj":"Chemical"},{"id":"342","span":{"begin":250,"end":253},"obj":"Chemical"},{"id":"343","span":{"begin":255,"end":270},"obj":"Chemical"}],"attributes":[{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"Gene:91653"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"MESH:C472082"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"MESH:C035596"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"MESH:D004126"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"MESH:D004126"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"MESH:D006851"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"MESH:C025223"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"MESH:C472082"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"MESH:C035596"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"MESH:D004126"},{"id":"A342","pred":"tao:has_database_id","subj":"342","obj":"MESH:D004126"},{"id":"A343","pred":"tao:has_database_id","subj":"343","obj":"MESH:D002264"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Scheme 2 Preparation of Substituted Acyloxymethylketones and Aminomethylketones\n(i) Boc-Leu-OH, HATU, NMM, N,N-dimethylformamide (DMF), 0 °C (64%), (ii) 4 M HCl/dioxane, (iii) HATU, 4-MeO-2-indolecarboxylic acid, NMM, DMF, 0 °C (61%), and (iv) CsF, DMF, carboxylic acid, 60 °C (43–91%)."}