PMC:7571312 / 102809-103839 JSONTXT

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LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T22 371-372 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 522-523 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 983-985 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T25 1022-1027 http://purl.obolibrary.org/obo/CLO_0007706 denotes M + H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T85128 77-83 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T16482 86-89 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T52838 120-126 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T7376 127-133 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T96266 134-139 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T8256 140-148 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T60449 150-163 Chemical denotes 3-methylbutyl http://purl.obolibrary.org/obo/CHEBI_30359
T28806 167-174 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T20881 175-184 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T98928 175-177 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T87171 178-184 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T83064 187-198 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T81926 219-238 Chemical denotes tert-butoxycarbonyl http://purl.obolibrary.org/obo/CHEBI_48502
T54816 250-256 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T52496 259-262 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T79162 293-299 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T50557 300-306 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T73976 310-327 Chemical denotes phenylalaninamide http://purl.obolibrary.org/obo/CHEBI_21371
T66397 465-473 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T28248 474-489 Chemical denotes dichloromethane http://purl.obolibrary.org/obo/CHEBI_15767
T23370 550-552 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T42571 567-571 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T80029 600-602 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T31051 626-628 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T39463 652-654 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T73098 666-668 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T11300 718-720 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T22367 770-772 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T29269 784-786 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T35866 810-812 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T13469 836-838 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T87006 850-852 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T56958 921-923 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T47490 940-942 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T39016 959-961 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T44950 983-985 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T574 0-391 Sentence denotes Following the procedure described for the preparation of N-((1S)-1-{[((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide but substituting N-(tert-butoxycarbonyl)-N-((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)-l-phenylalaninamide and making noncritical variations provided a crude green solid.
T575 392-549 Sentence denotes This material was purified by Biotage flash chromatography, eluting with methanol/dichloromethane to afford the title compound as a white solid, 300 mg, 91%.
T576 550-1030 Sentence denotes 1H NMR (400 MHz, DMSO-d6) δ 11.52 (d, J = 2.0 Hz, 1H), 8.68 (d, J = 7.8 Hz, 1H), 8.61 (d, J = 7.8 Hz, 1H), 7.61 (s, 1H), 7.37 (d, J = 7.1 Hz, 2H), 7.31 (d, J = 1.8 Hz, 1H), 7.26 (t, J = 7.6 Hz, 2H), 7.16 (t, J = 7.2 Hz, 1H), 7.07 (t, 1H), 6.97 (d, J = 8.1 Hz, 1H), 6.49 (d, J = 7.6 Hz, 1H), 4.68 (m, 1H), 4.38–4.49 (m, 3H), 3.88 (s, 3H), 2.97–3.17 (m, 4H), 2.20–2.32 (m, 1H), 2.02–2.14 (m, 1H), 1.93–2.02 (m, 1H), 1.52–1.69 (m, 2H); MS (APCI±) for C27H29N4O5Cl m/z 526.0 (M + H)−.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1896 465-473 Chemical denotes methanol MESH:D000432
1897 474-489 Chemical denotes dichloromethane MESH:D008752