PMC:7565482 / 11218-11920 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T50","span":{"begin":399,"end":402},"obj":"Body_part"},{"id":"T51","span":{"begin":511,"end":515},"obj":"Body_part"},{"id":"T52","span":{"begin":560,"end":567},"obj":"Body_part"},{"id":"T53","span":{"begin":662,"end":665},"obj":"Body_part"}],"attributes":[{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma84079"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma67847"}],"text":"To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. The search criteria were as follows: “linear peptide; blast option: 90%; Host: Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T39","span":{"begin":170,"end":178},"obj":"Disease"}],"attributes":[{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. The search criteria were as follows: “linear peptide; blast option: 90%; Host: Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T89","span":{"begin":84,"end":87},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9596"},{"id":"T90","span":{"begin":124,"end":129},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T91","span":{"begin":347,"end":354},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T92","span":{"begin":381,"end":393},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T93","span":{"begin":509,"end":515},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T94","span":{"begin":545,"end":546},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. The search criteria were as follows: “linear peptide; blast option: 90%; Host: Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions."}

{"project":"LitCovid-PubTator","denotations":[{"id":"141","span":{"begin":69,"end":82},"obj":"Species"},{"id":"142","span":{"begin":88,"end":99},"obj":"Species"},{"id":"143","span":{"begin":101,"end":118},"obj":"Species"},{"id":"144","span":{"begin":124,"end":129},"obj":"Species"},{"id":"145","span":{"begin":130,"end":143},"obj":"Species"},{"id":"146","span":{"begin":170,"end":180},"obj":"Species"},{"id":"147","span":{"begin":381,"end":393},"obj":"Species"}],"attributes":[{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"Tax:11118"},{"id":"A142","pred":"tao:has_database_id","subj":"142","obj":"Tax:11118"},{"id":"A143","pred":"tao:has_database_id","subj":"143","obj":"Tax:694002"},{"id":"A144","pred":"tao:has_database_id","subj":"144","obj":"Tax:9606"},{"id":"A145","pred":"tao:has_database_id","subj":"145","obj":"Tax:11118"},{"id":"A146","pred":"tao:has_database_id","subj":"146","obj":"Tax:2697049"},{"id":"A147","pred":"tao:has_database_id","subj":"147","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. The search criteria were as follows: “linear peptide; blast option: 90%; Host: Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions."}

{"project":"LitCovid-sentences","denotations":[{"id":"T69","span":{"begin":0,"end":301},"obj":"Sentence"},{"id":"T70","span":{"begin":302,"end":369},"obj":"Sentence"},{"id":"T71","span":{"begin":370,"end":380},"obj":"Sentence"},{"id":"T72","span":{"begin":381,"end":463},"obj":"Sentence"},{"id":"T73","span":{"begin":464,"end":581},"obj":"Sentence"},{"id":"T74","span":{"begin":582,"end":702},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. The search criteria were as follows: “linear peptide; blast option: 90%; Host: Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions."}