Results from the PLS-R analyses, conducted to understand the vehicle impact on the dissolution of the two drugs, are shown in Fig. 10. Fig. 10 Standardised coefficients corresponding to the variables studied for dissolution of montelukast, mesalazine and both drugs. Colour denotes coefficients with a moderate (lighter colour) and significant (darker colour) impact on the response (VIP > 0.7 and 1, respectively). (B.C., buffer capacity; ST, surface tension)