Table 3  Demographic characteristics and clinical and biological baseline characteristics.
Demographic Characteristics  All Patients (n = 45)  No Aspergillosis (n = 30)  Aspergillus Colonization (n = 8)  Putative/Probable Invasive Aspergillosis (n = 7)  p Value
Age, years  60 (53–71)  59 (54–68)  53 (51–71)  70 (63–75)  0.14
SexMen Women  32 (71.1)13 (28.9)  21 (70)9 (30)  7 (87.5)1 (12.5)  4 (57.1)3 (42.8)  0.42
BMI  27 (24.4–31.4)  27.5 (24.7–32.3)  27 (25.2–30.7)  25.2 (23.2–26.4)  0.99
Current smoking  3 (6.7)  2 (4.4)  0  1 (12.5)  0.54
Coexisting conditions
Any  31 (68.9)  19 (63)  6 (75)  6 (85.7)  0.47
Diabetes  17 (37.8)  12 (40)  3 (37.5)  2 (28.6)  0.74
Hypertension  15 (33.3)  7 (23.3)  5 (62.5)  3 (42.9)  0.1
Solid cancer  1 (2.2)  1 (3.3)  0  0  0.77
Hemopathy  2 (4.4)  1 (3.3)  0  1 (14.3)  0.54
Cardiovascular disease  3 (6.7)  3 (10)  2 (25)  2 (28.6)  0.34
Chronic obstructive pulmonary disease  0  0  0  0  -
Chronic kidney disease  4 (8.9)  2 (6.7)  1 (12.5)  1 (14.3)  0.83
Temperature (°C)  38 (37–38.9)  37.5 (337–38.4)  38.2 (37.9–39)  38.2 (37.7–38.8)  0.29
Heart rate (/min)  100 (80–110)  94 (80–110)  104 (100–110)  102 (85–119)  0.63
Systolic pressure  94 (87–107)  93 (85–105)  103 (100–109)  90 (82–102)  0.34
White blood cell count (109/L)  9.8 (6.8–12.9)  9.7 (6.9–13)  9.9 (7–10.7)  9.9 (6.7–12.9)  0.97
Neutrophil count (109/L)  7.9 (4.5–10.8)  7 (4.9–10.5)  8.5 (5.2–8.6)  5.6 (3.5–10.4)  0.8
Lymphocyte count (109/L)  0.81 (0.58–1.11)  0.83 (0.53–1.14)  0.7 (0.63–1.1)  0.72 (0.58–0.81)  0.87
Hemoglobin (g/L)  10.8 (9.5–12.5)  10 (9.4–12)  11.8 (10.6–13.6)  11 (10.5–13.6)  0.12
Platelet count (109/L)  264 (194–357)  282 (220–364)  244 (184–347)  162 (129–262)  0.12
Total bilirubin concentration (µmol/L)  8 (5.5–12)  8.5 (6–12)  11 (9–13)  7 (5.5–8)  0.72
Creatinine (µmol/L)  81 (53–162)  71 (51–109)  81 (73–173)  101 (82–184)  0.15
C-reactive protein (CRP) (mg/L)  157 (112–263)  155 (112–265)  112 (102–131)  112 (109–178)  0.03
Ratio of PaO2 to FiO2  152 (100–181)  164 (107–214)  120 (94–214)  136 (72–155)  0.25
SAPS II score on day 1  42 (31–57)  35 (30–58)  42 (21–55)  43 (35–82)  0.55
SOFA score on day 1  7 (2–11)  7 (4–10)  5 (2–10)  9 (2–12)  0.76
Data are presented as median (IQR: interquartiles), n (%). P values comparing Aspergillus colonization, invasive aspergillosis and no aspergillosis groups are tested by Kruskal–Wallis (continuous variables) or Chi-square test (categorical variables). Abbreviations: BMI: Body mass index; SAPS II: Simplified Acute Physiology Score II; SOFA: Sequential Organ Failure Assessment, PaO2: arterial oxygen tension.