yse Beta amyloid peptides (Zou et al., 2007, 2013). There is also increasing evidence that the RAAS system may be implicated in cancer. ACE2 was found to inhibit cancer cell growth, metastasis, and angiogenesis in breast (Yu et al., 2016; Zhang Q. et al., 2019), pancreatic (Zhou et al., 2011), and colon cancer (Bernardi et al., 2012). Another