Receptor tyrosine kinase inhibitors (eg, nintedanib) Vascular endothelial growth factor, platelet-derived growth factor, and fibroblast growth factor receptors Fibroblasts, pericytes, endothelial cells, cardiomyocytes Approved for treating pulmonary fibrosis Might be effective only at later stages and correct timing is unclear; frequent diarrhoea; risk of bleeding