Lesion location High AGP* Low AGP* Non-AGP Carious lesions limited to enamel Smooth surface N/A Resin infiltration Maximise fluoride during tooth brushing Topical fluoride therapy (Other remineralisation agents**) Occlusal surface N/A Resin fissure sealant ART/HVGIC sealant GIC sealant Approximal surface N/A Resin infiltration Fluoride (Other remineralisation agents**) Carious lesion extending into dentine or on root surface Smooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration NRCC SDF Occlusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration NRCC† SDF Approximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration Stainless steel crown (conventional placement) Zirconia crown Resin infiltration (outer 1/3 dentine) ART restoration† Hall Technique NRCC† SDF† Key: * = use rubber dam with sealant around tooth/dam interface and high-volume aspiration ** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth † = only for primary teeth ART = atraumatic restorative treatment CMCR = chemo-mechanical caries removal GIC = glass-ionomer cement HVGIC = high-viscosity glass-ionomer cement NRCC = non-restorative cavity control SDF = silver diamine fluoride