Variable Reference range, adults On admission ICU day 3 ICU day 7 ICU day 14 White blood cell (109/L) 4.50–9.80 9.58 13.99 24.14 23.58 C-reactive protein (mg/L) 0.0–5.0 137 77.7 138 121 Procalcitonin (mcg/L) 0.00–0.25 1.37 2.09 1.67 2.07 IL (interleukin)-6 (ng/L) < 3.4 491 32.7 NA NA Ferritin (mcg/L) 30–400 605 378 NA NA D-Dimer (mcg/L) 0.00–500.0 1605 810 3497 6941 Fibrinogen (g/L) 2.00–4.00 6.10 3.84 6.06 8.47 Activated partial-thromboplastin time (sec) 28.0–40.0 39 27.3 33.6 32.2 Creatinine (mg/dL) 0.51–0.95 2.4 5 2.9 2.6 Urea nitrogen (mg/dL) 21–54 90 172 135 167 Lactate dehydrogenase (U/L) 135–214 425 282 357 265 Arterial pH 7.35–7.45 7.36 7.35 7.23 7.34 Arterial partial pressure of oxygen (mmHg) 83–108 71.8 73.3 80.8 56.1 Arterial partial pressure of carbon dioxide (mmHg) 32–45 42.4 48.1 54.1 55.4 Lactate (mmol/L) 0.5–1.6 1.1 1.1 1.6 0.8 Nasopharyngeal swab Positive-quite positive-negative Positive Positive Positive Quite positive Ventilation mode Controlled Controlled Controlled Assisted Fraction of inspired oxygen 0.8 0.6 0.6 0.6 Positive end-expiratory pressure (cmH2O) 15 15 13 12 Continuous renal replacement therapy NO YES YES YES