Molecule  Binding affinity (kcal/mol)
RBD Spro  Mpro
Piperine  –6.4  –7.3
Chloroquine  –5.0  –4.9
Favipiravir  –5.3  –5.6
Hydroxychloroquine  –4.8  –6.0
Oseltamivir  –5.1  –5.5
Remdesivir  –6.1  –7.2
Ribavirin  –5.6  –6.1