Figure 7.  Radius of gyration plots of (a) RBD Spro (black) and RBD Spro-Piperine (red); (b) Mpro (black) and Mpro-Piperine (blue); (c) Intermolecular hydrogen bonds formed between RBD Spro-Piperine and Mpro-Piperine during 100 ns MD simulation.