Acknowledgements We sincerely thank the BioX Centre of IIT Mandi for use of different analytical instruments. AC thank Department of Science & Technology (DST) INSPIRE fellowship, for his research fellowship. The authors received no funding from an external source. Disclosure statement No potential conflicts of interest relevant to this article were reported. Author contributions AC conducted the majority of the experiments and analyzed the data. BD and SK conducted in silico studies. PM, designed the study and supervised the project. PM and AC, wrote the manuscript with support from BD, SK and BM. PM is the guarantor of this work and, as such, has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.