PMC:7536919 / 97-1212
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 66-70 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T2 | 188-197 | Body_part | denotes | (NK) cell | http://purl.org/sig/ont/fma/fma63147 |
T3 | 193-197 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T4 | 927-935 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
T5 | 930-935 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T6 | 1013-1023 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T7 | 1024-1028 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T2 | 135-143 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 247-255 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T4 | 336-343 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 438-445 | Disease | denotes | COVID19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T6 | 1097-1105 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 45-48 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T2 | 50-53 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
T3 | 64-70 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T4 | 188-197 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | (NK) cell |
T5 | 207-208 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T6 | 231-233 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
T7 | 318-319 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T8 | 421-422 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T9 | 614-615 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 699-700 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T11 | 761-762 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T12 | 927-935 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
T13 | 971-972 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T14 | 1024-1028 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 294-299 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T2 | 1040-1042 | Chemical | denotes | KL | http://purl.obolibrary.org/obo/CHEBI_74561 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 879-902 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune responses |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 0-144 | Sentence | denotes | It is widely reported in the literature that CD4, CD8 and total T cell count are significantly reduced in critically ill patients with COVID‐19. |
T6 | 145-265 | Sentence | denotes | Few weeks ago, we suggested natural killer (NK) cell count as a marker of severity in 34 hospitalized COVID‐19 patients. |
T7 | 266-384 | Sentence | denotes | On this topic, our research group firstly described a novel potential COVID19 severity marker, Krebs von den Lungen‐6. |
T8 | 385-525 | Sentence | denotes | This study aimed to investigate how a combination of COVID19 severity markers could be helpful in the clinical management of these patients. |
T9 | 526-797 | Sentence | denotes | The combination of these validated, reproducible and non‐expensive bioindicators showed a good accuracy in discriminating between severe and non‐severe patients, suggesting a promising value of this approach in the early prediction of a more aggressive disease phenotype. |
T10 | 798-1115 | Sentence | denotes | Despite its monocentric design, our study confirms the reliable dysregulation of innate immune responses, particularly involving NK cells, and suggests that surveillance of a peripheral biomarkers’ panel, including lymphocyte cell counts and KL‐6, may be useful in the clinical management of severe COVID‐19 patients. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
18 | 45-48 | Gene | denotes | CD4 | Gene:920 |
19 | 50-53 | Gene | denotes | CD8 | Gene:925 |
20 | 361-383 | Gene | denotes | Krebs von den Lungen‐6 | Gene:4582 |
21 | 1040-1044 | Gene | denotes | KL‐6 | Gene:4582 |
22 | 121-129 | Species | denotes | patients | Tax:9606 |
23 | 256-264 | Species | denotes | patients | Tax:9606 |
24 | 516-524 | Species | denotes | patients | Tax:9606 |
25 | 678-686 | Species | denotes | patients | Tax:9606 |
26 | 1106-1114 | Species | denotes | patients | Tax:9606 |
27 | 106-120 | Disease | denotes | critically ill | MESH:D016638 |
28 | 135-143 | Disease | denotes | COVID‐19 | MESH:C000657245 |
29 | 247-255 | Disease | denotes | COVID‐19 | MESH:C000657245 |
30 | 336-343 | Disease | denotes | COVID19 | MESH:C000657245 |
31 | 438-445 | Disease | denotes | COVID19 | MESH:C000657245 |
32 | 768-786 | Disease | denotes | aggressive disease | MESH:D001523 |
33 | 1097-1105 | Disease | denotes | COVID‐19 | MESH:C000657245 |