• Siltuximab for patients diagnosed with severe respiratory complications due to COVID-19 • Anti-IL-6 mitigation of cytokine storm • Observational retrospective cohort study • Cohort A: continuous positive airway pressure followed by siltuximab • Cohort B: intubation followed by siltuximab • Control group receiving continuous positive airway pressure or intubation only • N = 220 • Primary outcome of mortality over 30 days • Detailed siltuximab dosing regimen not specified. • Treatment procedure was based on clinicians judgement • Study completed May 8, 2020. Results pending (NCT04322188, 2020)