years of age with severe infection • Primary outcome of time to clinical improvement • N = 20 ruxolitinib + standard care • N = 21 placebo + standard care • Ruxolitinib 5 mg twice daily • Placebo vitamin C 100 mg twice daily • No difference in primary endpoint HR 1.669 (95% CI 0.836–3.335) • Improvement in lung computerized tomography (CT) scans • Significantl