The result of the pooled analysis of ischemic stroke due to LVO data is presented in Table 3. In summary, the total sample size was 39 patients. The mean age was 59.4 years with 26 (66.7%) males. The NIHSS at admission was 19.0 with an average of 1.5 involved vessels. 89.7% of the patients underwent MT with the majority (85%) using a Solumbra technique. On average, 2.3 attempts were required to retrieve the clot with 77.1% of cases achieving TICI 2B/3. Notably the complication rate was 15.4%, and the mortality rate was 45.9%.
Table 3. Pooled analysis: patient characteristics, treatment details, complications, and mortality for patients with LVO in the setting of COVID-19
No. of patients Mean age Male NIHSS Involved vessels MT treatment Solumbra No. of attempts TICI 2b/3 Complications Mortality
Wang et al.5 5 52.8 4 22.8 2.2 5 4 2.8 3 0 3
Escalard et al.7 10 59.5 8 22 1.5 10 NA 3.5 9 4 6
Valderrama et al.8 1 52 1 NA 3 1 NA NA 0 0 0
Avula et al.9 3 78.7 1 26 1.5 0 NA NA NA 0 3
Oxley et al.4 5 40.4 4 16.8 1 4 NA NA NA 0 0a
Current series 15 64.6 8 15.1 1.4 15 13 1.4 15 2 5
Total n – – 26 – – 35 17 – 27 6 17
Total N 39.0 39 39.0 38.0 39.0 39.0 20.0 30.0 35.0 39.0 37.0
Percentage/mean – 59.4 66.7 19.0 1.5 89.7 85.0 2.3 77.1 15.4 45.9
COVID-19: coronavirus disease 2019; LVO: Large Vessel Occlusion; MT: mechanical thrombectomy; NIHSS: National Institute of Health Stroke Scale; TICI: thrombolysis in cerebral infarction. aTwo patients were still in the hospital.