Exploring the relationship between non-invasive neuromodulation and the immune system in the context of a viral pandemic, although highly speculative, is also promising. While viral infections often lead to an important dysregulation of immune responses (Qin et al., 2020), neuromodulatory strategies that can down-regulate the excessive inflammation and its detrimental effects (Silverman et al., 2005) could show beneficial effects in the adjuvant treatment and even prevention of infection.