As it relates to tau imaging in the retina, there are currently no live imaging tools to specifically detect tau aggregates in the human retina. Preliminary results from a study that utilized spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescein (FAF) to visualize pathological tau aggregates in a cohort of PET-confirmed Alzheimer’s patients (Kayabasi, 2018) hints at the possibility of noninvasive live imaging and monitoring of neuropathological changes in the retina of MCI and AD patients; however, the specificity of the signal was not clear.