We gratefully acknowledge the authors and originating and submitting laboratories of the sequences from GISAID’s EpiCov Database on which this research is based. We thank Lionel Condé, Robert Gramzinski, Joshua Herbeck, Mélanie Merbah, Thembi Mdluli, Lydie Trautmann, Douglas Whalin, and Suzanne Wollen-Roberts. We also thank two reviewers for critical improvements of the original manuscript. This work was funded by US Department of Defense Health Agency and the US Department of the Army and a cooperative agreement between The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., and the US Department of the Army (W81XWH-18-2-0040). The views expressed are those of the authors and should not be construed to represent the positions of the US Army, the Department of Defense, or the Department of Health and Human Services.