The type A countries, with more than 1,000 COVID-19 cases per million in which the infection peaked before mid-April, were mostly the developed countries that had predominant cross-border human mobility in relatively cool and dry climates. The type B countries, with more than 1,000 COVID-19 cases per million in which the infection spread peaked after mid-June, were quasi-developed countries with BCG vaccination programs. The type C countries, with less than 1,000 COVID-19 cases per million in which the infection peaked before mid-April, were countries with high temperature and humidity that are characterized by lower cross-border mobility and more BCG vaccination. The type D countries, with less than 1,000 COVID-19 cases per million in which the infection spread peaked after mid-June, were mostly tropical developing countries with lower population density, less cross-border mobility, higher malaria incidence, and less BCG vaccination. These country-specific factors indicate that the COVID-19 spread is not simply driven by specific environmental variables, and the underlying mechanisms are complicated (Table 1). Therefore, evaluating the drivers of the COVID-19 spread at the present phase of disease expansion is a challenging task.