Table 1 Drivers of the COVID-19 spread in relation to the country types. Country types were defined by the patterns of COVID-19 spread (cases per 1 million population) (see Fig 3). Type A, countries that had a peak in the number of COVID-19 cases per week before the middle of April and had more than 1,000 COVID-19 cases per 1 million population; type B, countries that exhibited an increase in the number of COVID-19 cases per week after the middle of June and had more than 1,000 COVID-19 cases per 1 million population; type C, countries that had a peak in the number of COVID-19 cases per week before the middle of April and had less than 1,000 COVID-19 cases per 1 million population; and type D, countries that exhibited an increase in the number of COVID-19 cases per week after the middle of June and had less than 1,000 COVID-19 cases per 1 million population. The statistical significance of differences between the country types was tested by a Bonferroni’s multiple comparison test. Different letters indicate the values that are significantly different (p < 0.05) from each other. Factor Type A Type B Type C Type D Mean annual temperature 11.1 (±3.88) a 14.6 (±8.87) b 18.5 (±7.96) c 21.4 (±6.81) d Mean annual precipitation 865 (±368) a 806 (±541) a 1250 (±629) b 1290 (±869) b Population density 485 (±1060) 342 (±1400) 391 (±1500) 164 (±243) Relative frequency of visitors 154 (±329) a 36.1 (±65.4) b 73.8 (±97.4) b 16.4 (±27.2) b GDP per person 50200 (±21500) a 18500 (±18300) b 22200 (±18100) b 5690 (±5430) c BCG vaccination effect -1.37 (±1.42) a 0.752 (±1.37) b 0.467 (±1.51) b 0.88 (±0.694) b Relative frequency of people infected by malaria 0.163 (±1.26) a 2180 (±14200) a 2950 (±31800) a 40100 (±85000) b Relative frequency of people ≥ 65 years old 18.9 (±3.17) a 11.6 (±4.92) b 14.8 (±6.51) c 7.33 (±4.5) d