As previously mentioned, an urgent epidemiological effort has been undertaken to understand what risk factors are responsible for the principal outcome associated with COVID-19, i.e., mortality. From Chinese studies, mortality rates were increasing along age categories (mortality rate of 1.3% in the 50–59 range, 3.6% in the 60–69 range, 8% in the 70–79 range and 14.8% in the ≥range 80 years), the presence of cardiovascular diseases (10.5%), diabetes (7.3%), chronic respiratory diseases (6.3%), arterial hypertension (6%) and neoplasms (mortality 5.6%) [22,23]. In Italy, data from ISS—i.e., the Italian Health Institute—indicates that 1% of the patients who died did not suffer from any other diseases, 26% had only one disease, 26% had 2 diseases and 47% had 3 or more pathologic conditions. The most common chronic preexisting diseases in deceased patients were: arterial hypertension (70%), followed by diabetes mellitus (31.7%), chronic kidney disease CKD (23.1%), atrial fibrillation (22.5%), chronic obstructive pulmonary disease (COPD) (18.1%), the presence of an active cancer within the previous 5 years (16.8%), ischemic heart disease (16%) and obesity 10% [20]. It is very remarkable that CKD was present in more than 20% of the deceased patients due to COVID-19, also surpassing, in prevalence, those affected by COPD and/or those with an active cancer within the last 5 years.