Astroglial CCL5 and neuroprotection • gp120IIIB (X4)
• gp120BaL (R5) No • Morphine (10 μM)
• DAMGO • Morphine ↑ astroglial CCL5 blocking gp120BaL neurotoxicity
• Morphine (or CXCL12) does not block gp120IIIB neurotoxicity Rat, mixed neurons and glia; isolated neurons, astrocytes and microglia (Avdoshina et al. 2010)