, HIV-1 tg, female (Guo et al. 2012) SIV HIV Tat No Morphine (3 mg/kg i.m., q.i.d., 3 weeks) • ↑ miR-29b, ↓ PDGF-B mRNA, ↑ PDGF-BB with morphine and SIV • ↓ PDGF-B