The host's innate interferon (IFN) response is one key for controlling viral replication. The IFN response can be increased by administering artificial IFNs and IFN inducers. The recombinant IFN‐α and ‐β inhibited the replication of SARS‐ and MERS‐CoVs in animal models. 231  Several studies also described the combination of IFNs with antiviral drugs like ribavirin (180) or lopinavir‐ritonavir for treating SARS. 232 ,  233