PMC:7461420 / 86639-86838 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T410","span":{"begin":63,"end":67},"obj":"Disease"}],"attributes":[{"id":"A410","pred":"mondo_id","subj":"T410","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"These nucleoside analogs have shown remarkable potency against SARS‐CoV‐2 and other related CoVs in vitro and in vivo, with IC50 values in the low nanomolar range, outperforming remdesivir 3–10‐fold."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T42860","span":{"begin":6,"end":16},"obj":"Chemical"},{"id":"T44765","span":{"begin":178,"end":188},"obj":"Chemical"}],"attributes":[{"id":"A7592","pred":"chebi_id","subj":"T42860","obj":"http://purl.obolibrary.org/obo/CHEBI_33838"},{"id":"A65957","pred":"chebi_id","subj":"T44765","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"}],"text":"These nucleoside analogs have shown remarkable potency against SARS‐CoV‐2 and other related CoVs in vitro and in vivo, with IC50 values in the low nanomolar range, outperforming remdesivir 3–10‐fold."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2685","span":{"begin":63,"end":73},"obj":"Species"},{"id":"2686","span":{"begin":92,"end":96},"obj":"Species"},{"id":"2688","span":{"begin":6,"end":16},"obj":"Chemical"},{"id":"2689","span":{"begin":178,"end":188},"obj":"Chemical"}],"attributes":[{"id":"A2685","pred":"tao:has_database_id","subj":"2685","obj":"Tax:2697049"},{"id":"A2686","pred":"tao:has_database_id","subj":"2686","obj":"Tax:11118"},{"id":"A2688","pred":"tao:has_database_id","subj":"2688","obj":"MESH:D009705"},{"id":"A2689","pred":"tao:has_database_id","subj":"2689","obj":"MESH:C000606551"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"These nucleoside analogs have shown remarkable potency against SARS‐CoV‐2 and other related CoVs in vitro and in vivo, with IC50 values in the low nanomolar range, outperforming remdesivir 3–10‐fold."}

{"project":"LitCovid-sentences","denotations":[{"id":"T752","span":{"begin":0,"end":199},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"These nucleoside analogs have shown remarkable potency against SARS‐CoV‐2 and other related CoVs in vitro and in vivo, with IC50 values in the low nanomolar range, outperforming remdesivir 3–10‐fold."}